Nitric oxide: an emerging regulator of cell elongation during primary root growth

  1. Fernández-Marcos, María 1
  2. Sanz, Luis 1
  3. Lorenzo, Óscar 1
  1. 1 Dpto. de Fisiología Vegental; Centro Hispano-Luso de Investigaciones Agrarias (CIALE); Facultad de Biología; Universidad de Salamanca; Salamanca, Spain
Plant Signaling & Behavior

ISSN: 1559-2324

Year of publication: 2012

Volume: 7

Issue: 2

Pages: 196-200

Type: Article


More publications in: Plant Signaling & Behavior


Cited by

  • Web of Science Cited by: 0 (29-05-2023)
  • Dimensions Cited by: 57 (03-03-2023)

SCImago Journal Rank

  • Year 2012
  • SJR Journal Impact: 0.723
  • Best Quartile: Q2
  • Area: Plant Science Quartile: Q2 Rank in area: 107/417

Scopus CiteScore

  • Year 2012
  • CiteScore of the Journal : 2.0
  • Area: Plant Science Percentile: 62


(Data updated as of 03-03-2023)
  • Total citations: 57
  • Recent citations: 13
  • Relative Citation Ratio (RCR): 1.27
  • Field Citation Ratio (FCR): 5.67


Nitric oxide (NO) is a highly inducible molecule and overaccumulated during stress responses, such as drought, cold and pathogen infection. Several key developmental processes within a plant life cycle have been reported to be signaled by this gaseous molecule, and among them seed germination, de-etiolation, gravitropic response or root growth are well-characterized. The importance of NO as a plant growth and stress regulator is emerging considerably, despite the current knowledge about its signaling pathway is still limited. Therefore, the identification and characterization at the molecular level of NO targets is essential to get a deeper insight into this pathway. Here we characterize the effect of NO on root development in Arabidopsis and found that NO application reduces cell lengths in differentiation zone. Additionally, the contribution of the gibberellin (GA) signaling pathway to the NO root-related phenotypes, mainly through DELLA repressors, is also depicted.

Bibliographic References

  • Fern´ndez-Marcos M, Sanz L, Lewis DR, Muday GK, Lorenzo O. Nitric oxide causes root apical meristem defects and growth inhibition while reducing PIN-FORMED 1 (PIN1)-dependent acropetal auxin transport. Proc Natl Acad Sci U S A 2011; 108:18506 - 11;; PMID: 22021439
  • Correa-Aragunde N, Graziano M, Lamattina L. Nitric oxide plays a central role in determining lateral root development in tomato. Planta 2004; 218:900 - 5;; PMID: 14716561
  • Pagnussat GC, Simontacchi M, Puntarulo S, Lamattina L. Nitric oxide is required for root organogenesis. Plant Physiol 2002; 129:954 - 6;; PMID: 12114551
  • He Y, Tang RH, Hao Y, Stevens RD, Cook CW, Ahn SM, et al. Nitric oxide represses the Arabidopsis floral transition. Science 2004; 305:1968 - 71;; PMID: 15448272
  • Hu X, Neill SJ, Tang Z, Cai W. Nitric oxide mediates gravitropic bending in soybean roots. Plant Physiol 2005; 137:663 - 70;; PMID: 15681661
  • Stöhr C, Stremlau S. Formation and possible roles of nitric oxide in plant roots. J Exp Bot 2006; 57:463 - 70;; PMID: 16356940
  • Ille´s P, Schlicht M, Pavlovkin J, Lichtscheidl I, Baluska F, Ovecka M. Aluminium toxicity in plants: internalization of aluminium into cells of the transition zone in Arabidopsis root apices related to changes in plasma membrane potential, endosomal behaviour, and nitric oxide production. J Exp Bot 2006; 57:4201 - 13;; PMID: 17085753
  • Ishikawa H, Evans ML. Specialized zones of development in roots. Plant Physiol 1995; 109:725 - 7; PMID: 11539165
  • Masson PH. Root gravitropism. Bioessays 1995; 17:119 - 27;; PMID: 7748162
  • Blancaflor EB, Masson PH. Plant gravitropism. Unraveling the ups and downs of a complex process. Plant Physiol 2003; 133:1677 - 90;; PMID: 14681531
  • Kasprowicz A, Szuba A, Volkmann D, Baluska F, Wojtaszek P. Nitric oxide modulates dynamic actin cytoskeleton and vesicle trafficking in a cell type-specific manner in root apices. J Exp Bot 2009; 60:1605 - 17;; PMID: 19261922
  • Cowling RJ, Harberd NP. Gibberellins control Arabidopsis hypocotyl growth via regulation of cellular elongation. J Exp Bot 1999; 50:1351 - 7;
  • de Lucas M, Davière JM, Rodri´guez-Falco´n M, Pontin M, Iglesias-Pedraz JM, Lorrain S, et al. A molecular framework for light and gibberellin control of cell elongation. Nature 2008; 451:480 - 4;; PMID: 18216857
  • Beligni MV, Lamattina L. Nitric oxide stimulates seed germination and de-etiolation, and inhibits hypocotyl elongation, three light-inducible responses in plants. Planta 2000; 210:215 - 21;; PMID: 10664127
  • Lozano-Juste J, Leo´n J. Nitric oxide regulates DELLA content and PIF expression to promote photomorphogenesis in Arabidopsis. Plant Physiol 2011; 156:1410 - 23;; PMID: 21562334
  • Fu X, Harberd NP. Auxin promotes Arabidopsis root growth by modulating gibberellin response. Nature 2003; 421:740 - 3;; PMID: 12610625