Genomic profile of sporadic colorectal cancer liver metastases versus primary tumors as defined by high-density microarray techniques

  1. José María Sayagués 1
  2. Luís Antonio Corchete 2
  3. María Laura Gutiérrez 1
  4. Maria Eugenia Sarasquete 2
  5. María del Mar Abad 3
  6. Oscar Bengoechea 3
  7. Encarna Fermiñán 4
  8. María Fernanda Anduaga 5
  9. Sofia del Carmen 3
  10. Manuel Iglesias 5
  11. Carmen Esteban 5
  12. María Angoso 5
  13. Jose Antonio Alcazar 5
  14. Jacinto García 5
  15. Alberto Orfao 1
  16. Luís Muñoz-Bellvis 5
  1. 1 Cytometry Service-NUCLEUS, Department of Medicine, Cancer Research Center (IBMCC-CSIC/USAL) and IBSAL (University of Salamanca)
  2. 2 Cáncer Research Center and Service of Hematology (University Hospital of Salamanca)
  3. 3 Department of Pathology (University Hospital of Salamanca)
  4. 4 Genomics Unit, Cancer Research Center (IBMCC-CSIC/USAL)
  5. 5 Service of General and Gastrointestinal Surgery and IBSAL (University Hospital of Salamanca); Salamanca, Spain
Journal:
Journal of Medical Discovery

ISSN: 2476-129X

Year of publication: 2016

Volume: 1

Issue: 1

Type: Article

DOI: 10.24262/JMD.1.1.16003 GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Journal of Medical Discovery

Bibliographic References

  • Van CE, Cervantes A, Adam R, Sobrero A, van Krieken JH, Aderka D, et al. ESMO consensus guidelines for the management of patients with metastatic colorectal cancer. Ann Oncol 2016 Aug;27(8):1386-422.
  • Weitz J, Koch M, Debus J, Hohler T, Galle PR, Buchler MW. Colorectal cancer. Lancet 2005 Jan 8;365(9454):153-65.
  • Nguyen DX, Massague J. Genetic determinants of cancer metastasis. Nat Rev Genet 2007 May;8(5):341-52.
  • Sayagues JM, Fontanillo C, Abad MM, Gonzalez M, Sarasquete ME, Chillon MC, et al. Mapping of genetic abnormalities of primary tumours from metastatic CRC by high-resolution SNP arrays. PLoS ONE. 2010 Oct 29;5(10):e13752.
  • Sayagues JM, Abad MM Barquero H, Gutierrez ML, Gónzalez-Gónzalez M, Jensen E, Bengoechea O, et al. Intratumoral cytogenetic heterogeneity of sporadic colorectal carcinomas suggests several pathways to liver metastasis. J Pathol. 2010 Jul;221(3):308-19.
  • Mudduluru G, Abba M, Batliner J, Patil N, Scharp M, Lunavat TR, et al. A Systematic Approach to Defining the microRNA Landscape in Metastasis. Cancer Res 2015 Aug 1;75(15):3010-9.
  • Lin AY, Chua MS, Choi YL, Yeh W, Kim YH, Azzi R, et al. Comparative profiling of primary colorectal carcinomas and liver metastases identifies LEF1 as a prognostic biomarker. PLoS ONE 2011;6(2):e16636.
  • Vignot S, Lefebvre C, Frampton GM, Meurice G, Yelensky R, Palmer G, et al. Comparative analysis of primary tumour and matched metastases in colorectal cancer patients: evaluation of concordance between genomic and transcriptional profiles. Eur J Cancer 2015 May;51(7):791-9.
  • Roessler S, Lin G, Forgues M, Budhu A, Hoover S, Simpson RM, et al. Integrative genomic and transcriptomic characterization of matched primary and metastatic liver and colorectal carcinoma. Int J Biol Sci 2015;11(1):88-98.
  • Gonzalez-Gonzalez M, Fontanillo C, Abad MM, Gutierrez ML, Mota I, Bengoechea O, et al. Identification of a characteristic copy number alteration profile by high-resolution single nucleotide polymorphism arrays associated with metastatic sporadic colorectal cancer. Cancer 2014 Jul 1;120(13):1948-59.
  • Gonzalez-Gonzalez M, Munoz-Bellvis L, Mackintosh C, Fontanillo C, Gutierrez ML, Abad MM, et al. Prognostic Impact of del(17p) and del(22q) as assessed by interphase FISH in sporadic colorectal carcinomas. PLoS ONE 2012;7(8):e42683.
  • Kelley RK, Van Bebber SL, Phillips KA, Venook AP. Personalized medicine and oncology practice guidelines: a case study of contemporary biomarkers in colorectal cancer. J Natl Compr Canc Netw 2011 Jan;9(1):13-25.
  • Kopetz S, Tabernero J, Rosenberg R, Jiang ZQ, Moreno V, Bachleitner-Hofmann T, et al. Genomic classifier ColoPrint predicts recurrence in stage II colorectal cancer patients more accurately than clinical factors. Oncologist 2015 Feb;20(2):127-33.
  • Sayagues JM, Corchete LA, Gutierrez ML, Sarasquete ME, del Mar AM, Bengoechea O, et al. Genomic characterization of liver metastases from colorectal cancer patients. Oncotarget 2016 Sep 20.
  • Maierthaler M, Benner A, Hoffmeister M, Surowy H, Jansen L, Knebel P, et al. Plasma miR-122 and miR-200 family are prognostic markers in colorectal cancer. Int J Cancer 2016 Sep 15.
  • Liu Y, Zhou J, Zhang C, Fu W, Xiao X, Ruan S, et al. HLJ1 is a novel biomarker for colorectal carcinoma progression and overall patient survival. Int J Clin Exp Pathol 2014;7(3):969-77.
  • Peng X, Luo Z, Kang Q, Deng D, Wang Q, Peng H, et al. FOXQ1 mediates the crosstalk between TGF-beta and Wnt signaling pathways in the progression of colorectal cancer. Cancer Biol Ther 2015;16(7):1099-109.