SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRASG12D inhibitor in KRAS LUAD

  1. Baltanás, F.C.
  2. Kramer-Drauberg, M.
  3. García-Navas, R.
  4. Patrucco, E.
  5. Petrini, E.
  6. Arnhof, H.
  7. Olarte-San Juan, A.
  8. Rodríguez-Ramos, P.
  9. Borrajo, J.
  10. Calzada, N.
  11. Castellano, E.
  12. Mair, B.
  13. Kostyrko, K.
  14. Hofmann, M.H.
  15. Ambrogio, C.
  16. Santos, E.
Journal:
Proceedings of the National Academy of Sciences of the United States of America

ISSN: 1091-6490 0027-8424

Year of publication: 2025

Volume: 122

Issue: 11

Type: Article

DOI: 10.1073/PNAS.2422943122 GOOGLE SCHOLAR lock_openOpen access editor