Publications (5) Publications in which a researcher has participated

filter_list Anesthesiology

2023

  1. Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids

    Acta Pharmaceutica Sinica B, Vol. 13, Núm. 1, pp. 82-99

2021

  1. Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ1Receptor Antagonists for the Treatment of Pain

    Journal of Medicinal Chemistry, Vol. 64, Núm. 14, pp. 10139-10154

2020

  1. Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ1Receptor Antagonist Clinical Candidate for the Treatment of Pain

    Journal of Medicinal Chemistry, Vol. 63, Núm. 24, pp. 15508-15526

  2. EST64454: A Highly Soluble σ1Receptor Antagonist Clinical Candidate for Pain Management

    Journal of Medicinal Chemistry, Vol. 63, Núm. 23, pp. 14979-14988

2017

  1. 5-HT modulates the rat mesenteric vasopressor outflow by 5-HT1D sympatholytic receptors

    Clinical and Experimental Pharmacology and Physiology, Vol. 44, Núm. 12, pp. 1224-1231