María Carmen
Guerrero Arroyo
Catedrática de Universidad
Publications (63) María Carmen Guerrero Arroyo publications
2024
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Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice
Cell Communication and Signaling, Vol. 22, Núm. 1
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Platelet C3G: a key player in vesicle exocytosis, spreading and clot retraction
Cellular and Molecular Life Sciences, Vol. 81, Núm. 1
2023
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Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms
Cell Communication and Signaling, Vol. 21, Núm. 1
2022
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C3G down-regulation enhances pro-migratory and stemness properties of oval cells by promoting an epithelial-mesenchymal-like process
International journal of biological sciences, Vol. 18, Núm. 15, pp. 5873-5884
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New functions of C3G in platelet biology: Contribution to ischemia-induced angiogenesis, tumor metastasis and TPO clearance
Frontiers in Cell and Developmental Biology, Vol. 10
2021
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C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells
Cell Death and Disease, Vol. 12, Núm. 4
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C3G protein, a new player in glioblastoma
International Journal of Molecular Sciences, Vol. 22, Núm. 18
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C3G self-regulatory mechanism revealed: implications for hematopoietic malignancies
Molecular and Cellular Oncology
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Characterization of the platelet phenotype caused by a germline RUNX1 Variant in a CRISPR/Cas9-generated murine model
Thrombosis and Haemostasis, Vol. 121, Núm. 9, pp. 1193-1205
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Contribution of c3g and other gefs to liver cancer development and progression
Hepatoma Research, Vol. 7
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Terapia antiplaquetaria en cáncer
Farmajournal, Vol. 6, Núm. 2, pp. 63-73
2020
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Análisis del polimorfismo CYP2C19*2 en la población castellanoleonesa
Farmajournal, Vol. 5, Núm. 1, pp. 95-104
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C3G contributes to platelet activation and aggregation by regulating major signaling pathways
Signal Transduction and Targeted Therapy, Vol. 5, Núm. 1
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C3G is upregulated in hepatocarcinoma, contributing to tumor growth and progression and to HGF/MET pathway activation
Cancers, Vol. 12, Núm. 8, pp. 1-22
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Mechanisms of autoregulation of C3G, activator of the GTPase Rap1, and its catalytic deregulation in lymphomas
Science signaling, Vol. 13, Núm. 647
2018
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C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation
Cell Communication and Signaling, Vol. 16, Núm. 1
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How Rap and its GEFs control liver physiology and cancer development. C3G alterations in human hepatocarcinoma
HEPATIC ONCOLOGY, Vol. 5, Núm. 1
2017
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C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis
Oncotarget, Vol. 8, Núm. 67, pp. 110994-111011
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The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia
Oncotarget, Vol. 8, Núm. 16, pp. 26027-26040
2016
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C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
Oncotarget, Vol. 7, Núm. 29, pp. 45060-45078