Publications (36) Alberto Fernández Medarde publications

2024

  1. Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice

    Cell Communication and Signaling, Vol. 22, Núm. 1

2023

  1. GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina

    Cells, Vol. 12, Núm. 21

  2. Optimized Protocol for Isolation and Culture of Murine Neonatal Primary Lung Fibroblasts

    Methods and Protocols, Vol. 6, Núm. 1

  3. PKD phosphorylation and COP9/Signalosome modulate intracellular Spry2 protein stability

    Oncogenesis, Vol. 12, Núm. 1

2022

  1. Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia

    Cancers, Vol. 14, Núm. 16

2021

  1. 40 years of RAS-a historic overview

    Genes, Vol. 12, Núm. 5

  2. Anthraquinones as inhibitors of SOS RAS-GEF activity

    Biomolecules, Vol. 11, Núm. 8

  3. Ras GEF Mouse Models for the Analysis of Ras Biology and Signaling

    Methods in Molecular Biology (Humana Press Inc.), pp. 361-395

  4. The reversed intra- and extracellular pH in tumors as a unified strategy to chemotherapeutic delivery using targeted nanocarriers

    Acta Pharmaceutica Sinica B, Vol. 11, Núm. 8, pp. 2243-2264

2019

  1. Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice

    Cell Death and Disease, Vol. 10, Núm. 11

  2. The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein

    Oncogenesis, Vol. 8, Núm. 1

2018

  1. Spatial learning and long-term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice

    Brain and Behavior, Vol. 8, Núm. 11

2017

  1. Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus

    Molecular and Cellular Neuroscience, Vol. 85, pp. 127-147

2016

  1. A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males

    Journal of Psychiatry and Neuroscience, Vol. 41, Núm. 3, pp. 192-202

  2. Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs

    Oncogene, Vol. 35, Núm. 50, pp. 6389-6402

2015

  1. Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

    European Journal of Pharmaceutics and Biopharmaceutics, Vol. 93, pp. 52-79

2014

  1. Rasgrf2 controls dopaminergic adaptations to alcohol in mice

    Brain Research Bulletin, Vol. 109, pp. 143-150

  2. Rasgrf2 controls noradrenergic involvement in the acute and subchronic effects of alcohol in the brain

    Psychopharmacology, Vol. 231, Núm. 21, pp. 4199-4209

  3. Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells

    BMC Genomics, Vol. 15, Núm. 1

2012

  1. RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 51, pp. 21128-21133