Publications by the researcher in collaboration with Xosé R. Bustelo (20)

2023

  1. Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors

    Oncogene, Vol. 42, Núm. 5, pp. 389-405

2022

  1. The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function

    Oncogene, Vol. 41, Núm. 24, pp. 3341-3354

  2. Hematopoietic Cells Influence Vascular Development in the Retina

    Cells, Vol. 11, Núm. 20

  3. Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model

    Molecular Oncology, Vol. 16, Núm. 19, pp. 3533-3553

  4. A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors

    Cell Reports, Vol. 38, Núm. 11

2021

  1. Functional specificity of the members of the sos family of ras‐gef activators: Novel role of sos2 in control of epidermal stem cell homeostasis

    Cancers, Vol. 13, Núm. 9

  2. Distinct roles of vav family members in adaptive and innate immune models of arthritis

    Biomedicines, Vol. 9, Núm. 6

  3. Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis

    EMBO Journal, Vol. 40, Núm. 22

2020

  1. Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor

    Oncogene, Vol. 39, Núm. 28, pp. 5098-5111

  2. Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis

    Nature Communications, Vol. 11, Núm. 1

  3. VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma

    Nature Communications, Vol. 11, Núm. 1

2019

  1. Vagal afferents contribute to sympathoexcitation-driven metabolic dysfunctions

    Journal of Endocrinology, Vol. 240, Núm. 3, pp. 483-496

2018

  1. R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes

    Science Signaling, Vol. 11, Núm. 532

  2. Differential role of the RasGEFs Sos1 and Sos2 in mouse skin homeostasis and carcinogenesis

    Molecular and Cellular Biology, Vol. 38, Núm. 16

2017

  1. A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia

    Cancer Cell, Vol. 32, Núm. 5, pp. 608-623.e9

2013

  1. The Rho Exchange Factors Vav2 and Vav3 Favor Skin Tumor Initiation and Promotion by Engaging Extracellular Signaling Loops

    PLoS Biology, Vol. 11, Núm. 7

2012

  1. The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development

    Molecular Biology of the Cell, Vol. 23, Núm. 12, pp. 2373-2387

2011

  1. Transcriptional factor Aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogene

    Journal of Biological Chemistry, Vol. 286, Núm. 4, pp. 2896-2909

2009

  1. The use of knockout mice reveals a synergistic role of the vav1 and rasgrf2 gene deficiencies in lymphomagenesis and metastasis

    PLoS ONE, Vol. 4, Núm. 12

2007

  1. RasGRF2, a Guanosine Nucleotide Exchange Factor for Ras GTPases, participates in T-cell signaling responses

    Molecular and Cellular Biology, Vol. 27, Núm. 23, pp. 8127-8142