Administración intraventricular de morfina en el tratamiento del dolor orofacial maligno

  1. J. Anaya
  2. Guillermo García March
  3. María José Sánchez Ledesma
  4. J. Martínez-Alegría
  5. J. Broseta
Journal:
Revista española de cirugía oral y maxilofacial: Publicación Oficial de la Sociedad Española de Cirugía Oral y Maxilofacial

ISSN: 1130-0558

Year of publication: 1988

Volume: 10

Issue: 3

Pages: 171-174

Type: Article

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More publications in: Revista española de cirugía oral y maxilofacial: Publicación Oficial de la Sociedad Española de Cirugía Oral y Maxilofacial

Abstract

In 23 cases presenting with intractable orofaciocervical malign pain, small doses of morphine were injected in the lateral ventricle through an Ommaya type reservoir placed subcutaneously. After a mean follow-up of 2-3 months a satisfactory 50 to 100% pain relief was obtained in 18 patients. The more effective free of side-effects dose of morphine was 0,3 mg/ml. In 16 patients developed diverse degrees of tolerance to morphine, generally related to previous parenteral or intrathecal administration of morphine. Side-effects were minimal and transitory, with no occurrence of respiratory depression

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