Cuidados de la piel tras el tratamiento oncológico

  1. HERNÁNDEZ GUIO, Ana 1
  2. ZARZUELO CASTAÑEDA, Aránzazu 2
  3. SÁNCHEZ MARTÍN, Almudena 3
  1. 1 Hospital Clínico Universitario de Salamanca
  2. 2 Departamento de Ciencias Farmacéuticas, Área Farmacia y Tecnología Farmacéutica. Campus Miguel de Unamuno. Salamanca
  3. 3 Hospital Universitario de Salamanca
    info

    Hospital Universitario de Salamanca

    Salamanca, España

    ROR https://ror.org/0131vfw26

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Zeitschrift:
Farmajournal

ISSN: 2445-1355

Datum der Publikation: 2017

Ausgabe: 2

Nummer: 2

Seiten: 127-136

Art: Artikel

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Andere Publikationen in: Farmajournal

Zusammenfassung

Skin lesions decrease the quality of life of cancer patients, mood, adherence and tolerance to treatment, being necessary sometimes reduce the dose or even disrupt drug therapy. The objective is to describe and estimate the incidence of cutaneous adverse effects in patients treated with oral antineoplastic, and design and implement an oncology pharmaceutical care program to prevent and manage this cutaneous toxicity. 5 months retrospective descriptive study of patients treated with oral antineoplastic in a university hospital in Spain, evaluation of results of previous descriptive study and design pharmaceutical care program (interviews and algorithm) and preparing of educational materials (brochures). Of 549 patients, 131 (23.86%) had cutaneous adverse effects, mainly hand-foot syndrome (35.96%). Of 25 drugs analyzed, 21 were related with effects, highlighting the incidence with axitinib (100%).There is a high incidence of cutaneous adverse effects in patients treated with oral antineoplastic, which could decrease their quality of life and even disrupt drug therapy. It is therefore necessary to develop pharmaceutical care programs to inform, educate and support to cancer patients about these adverse effects.

Bibliographische Referenzen

  • Allevato M. Efectos adversos cutáneos de la terapia antineoplásica. Act Terap Dermatol. 2008; 31:78.
  • Bensadoun RJ, Humbert P, Krutman J, Luger T, Triller R, Rougier A, et al. Daily baseline skin care in the prevention, treatment, and supportive care of skin toxicity in oncology patients: recommendations from a multinational expert panel. Cancer Manag Res. 2013 Dec 9;5:401-8. doi:10.2147/CMAR.S52256.
  • eCollection 2013. PubMed PMID: 24353440. PubMed Central PMCID: PMC3862511.
  • Byun HJ, Lee HJ, Yang JI, Kim KH, Park KO, Park SM, et al. Daily skin care habits and the risk of skin eruptions and symptoms in cancer patients. Ann Oncol. 2012 Aug; 23(8):1992-8. doi: 10.1093/annonc/mds141. Epub 2012 Jun 13. PubMed PMID: 22700992.
  • Cancer.gov [Internet]. EEUU: Instituto Nacional del Cáncer de los Institutos Nacionales de la Salud de los EEUU; 2015 [consultado el 22 de abril 2015]. Disponible en: http://www.cancer.gov/espanol/cancer/tratamiento/efectos-secundarios
  • Cancer.gov [Internet] EEUU: Instituto Nacional del Cáncer de los Institutos Nacionales de la Salud de los EEUU; 2009 [consultado el 10 de mayo de 2016]. Disponible en: http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf
  • Cancer.net [Internet]. EEUU: Sociedad Estadounidense de Oncología Clínica, ASCO; 2005 [consultado el 14 de marzo de 2016]. Disponible en:http://www.cancer.net/es/desplazarse-por-atenci%C3%B3n-del-c%C3%A1ncer/efectos-secundarios/s%C3%ADndrome-mano-pie-o-eritrodisestesia-palmoplantar
  • Dreno B, Bensadoun RJ, Humbert P, Krutmann J, Luger T, Triller R, et al. Algorithm for dermocosmetic use in the management of cutaneous side-effects associated with targeted therapy in oncology. J Eur Acad Dermatol Venereol. 2013 Sep; 27(9):1071-80. doi: 10.1111/jdv.12082. Epub 2013 Feb 1. PubMed PMID: 23368717. PubMed Central PMCID: PMC3883088.
  • Eucerin [Internet] España: Eucerin; 2016 [consultado el 12 de mayo de 2016]. Disponible en: http://www.eucerin.es/acerca-de-la-piel/conocimientos-basicos-sobre-la-piel/piel-masculina-y-piel-femenina
  • Jaén P, Truchuelo T, Sanmartín O, Soto J y AECC. El cáncer y la piel. Guía de cuidados dermatológicos del paciente oncológico. Madrid: AECC; 2012.
  • Mellídez Barroso JC, Costa T, Julião I, Domingues D. Alteraciones cutáneas inducidas por terapéuticas moleculares dirigidas (I), inhibidores EGFR. REGIO. 2012; 01:13-22.
Fuente de los datos: Dialnet