Interleukina 18, ¿nuevo factor a tener en cuenta en la patogénesis de la enfermedad periodontal?
- Andrés García, Rodrigo
- Amaro, J.
- Bascones Martínez, Antonio
ISSN: 1699-6585
Datum der Publikation: 2006
Ausgabe: 18
Nummer: 2
Seiten: 91-100
Art: Artikel
Andere Publikationen in: Avances en periodoncia e implantología oral
Zusammenfassung
Periodontal disease is an inflammatory, chronic and infectious process,where the tooth support tissues get lost.There is an agreement that bacteria are responsible for the beginning and support of the disease. It is believed that the type of individual immune response, is responsible for the periodontal destruction degree. It is thought that an immune response regulated by antibodies would produce a larger tissue destruction, due to the hyperstimulation of the immune system. While cellular immune response would be more protective with periodontal tissues. In this paper, we suggest that interleukin 18 (IL-18), as an interferon gamma inductor, would favor the cellular immune response development, allowing a more efficient bacterial elimination, reducing the periodontal tissue damage.