Regulación génica en Streptomyces

  1. Ramón Santamaría 1
  2. Margarita Díaz 1
  3. Laura Sevillano 1
  4. Sergio Antoraz 1
  5. Ricardo Sánchez de la Nieta 1
  6. Marta González 1
  7. Ana M. Martínez 1
  1. 1 Instituto de Biología Funcional y Genómica. Consejo superior de Investigaciones Científicas/ Universidad de Salamanca
Revista:
SEM@foro

ISSN: 2254-4399

Año de publicación: 2017

Título del ejemplar: https://www.semicrobiologia.org/revista-semaforo/junio-2017

Número: 63

Páginas: 43-44

Tipo: Artículo

Otras publicaciones en: SEM@foro

Referencias bibliográficas

  • Sevillano L., Vijgenboom E., van Wezel GP., Díaz, M, and Santamaría, R. I. (2016) New approaches to achieve high level enzyme production in Streptomyces. Microbial Cell Factories 15:28.
  • Rodríguez, H., Rico, S., Yepes, A., Franco-Echevarria, E., Antoraz, S., Santamaría, R. I. and Díaz, M. (2015). The two kinases, AbrC1 and AbrC2, of the atypical two-componentsystem AbrC are needed to regulate antibiotic production and differentiation in Streptomyces coelicolor. Frontiers in Microbiology 6:450 doi: 10.3389/fmicb.2015.00450.
  • Antoraz, S., Santamaría, R.I., Díaz, M., Sanz, D. and Rodríguez, H. (2015) Toward a new focus in antibiotic and drug discovery from the Streptomyces Arsenal. Frontiers in Microbiology 6:461 doi: 10.3389/ fmicb.2015.00461.
  • Rico S., Yepes, A., Rodríguez, H., Santamaría, J., Antoraz, S., Krause, E., Díaz, M and Santamaría, RI. (2014 a). “Regulation of the AbrA1/A2 two-component system in Streptomyces coelicolor and the potential of its deletion strain as a heterologous host for antibiotic production.” PLOS One 9:e109844.
  • Rico S, Santamaría RI, Yepes A, Rodríguez H, Laing E, Bucca G, Smith CP, Díaz M. (2014b). “Deciphering the regulon of the Streptomyces coelicolor AbrC3, a positive response regulator of antibiotic production. Appl. Environ. Microbiology 80(8): 2417-2428.
  • Rodríguez, H., Rico, S., Díaz, M. and Santamaría, RI. (2013). “Two-component systems in Streptomyces: key regulators of antibiotic complex pathways”. Microbial Cell Factories 12:127.
  • Sevillano, L., Díaz, M. and Santamaría, RI. (2013). “Stable expression plasmids for Streptomyces based on a toxin-antitoxin system” Microbial Cell Factories 12:39.
  • Díaz, M., Sevillano, L., Rico, S., Lombo, F., Braña, AF., Salas, JA., Méndez, C. and Santamaría, RI. (2013). “High level of antibiotic production in a double polyphosphate kinase and phosphate-binding protein mutant of Streptomyces lividans “. FEMS letters 342, 123-129.
  • Sevillano L., Díaz, M. and Santamaría, RI. (2012). Identification of the first functional toxin-antitoxin system in Streptomyces. PloS One 7(3): e32977.
  • Yepes, A., Rico, S., Rodríguez, A., Santamaría, RI. and Díaz, M. (2011). “Novel two-components systems involved in antibiotic regulation in Streptomyces coelicolor”. PloS One 6(5): e19980.
  • Pérez, J, Muñoz-Dorado J, Braña AF, Shimkets L J, Sevillano L and Santamaría RI. (2011). “Myxococcus xanthus induces actinorhodin overproduction and aerial mycelium formation by Streptomyces coelicolor”. Microbial Biotechnology 4:175-183.
  • Esteban A, Díaz M, Yepes A and Santamaría RI. (2008). “Expression of the pstS gene of Streptomyces lividans is regulated by the carbon source and is partially independent of the PhoP regulator.” BMC Microbiology 8:201 doi:10.1186/1471-2180-8-201.
  • Díaz, M., Ferreras, E., Moreno, R., Yepes, A., Berenguer, J, and Santamaría, RI., (2008). “High-level overproduction of Thermus enzymes in Streptomyces lividans.” Applied Microbiology and Biotechnology 79, 1001-1008.