Carcinoma de pulmón no microcítico

  1. López, A. 1
  2. Escalera, E. 1
  3. Del Barco, E. 1
  4. Bellido, L. 1
  5. Cigarral, B. 1
  6. Barrios, B. 1
  7. Casado, D. 1
  8. Claros, J. 1
  9. Figuero, L. 1
  10. Olivares, A. 1
  11. Terán, E. 1
  12. Cruz, J.J. 1
  1. 1 Instituto de Investigación Biomédica de Salamanca (IBSAL), Servicio de Oncología Médica, Complejo Asistencial Universitario de Salamanca (CAUSA), Salamanca, España
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2021

Título del ejemplar: Enfermedades oncológicas (II)Tumores torácicos. Cáncer de cabeza y cuello

Serie: 13

Número: 25

Páginas: 1377-1387

Tipo: Artículo

DOI: 10.1016/J.MED.2021.02.002 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

Las neoplasias pulmonares son la primera causa de muerte por cáncer en el mundo. La incidencia y la mortalidad de esta enfermedad se correlacionan estrechamente con su principal factor etiológico, el tabaco. El adenocarcinoma es el subtipo histológico diagnosticado con más frecuencia, seguido del carcinoma epidermoide, el carcinoma de células grandes y el carcinoma microcítico de pulmón, que se engloba dentro de los carcinomas neuroendocrinos. Debido a los avances realizados en la investigación de terapias diana en los últimos años, resulta de gran importancia el estudio de puntos de control inmunitario y de mutaciones oncogénicas específicas que pueden modificar la actitud terapéutica del tumor, especialmente en las variantes de adenocarcinoma. Llevar a cabo una adecuada estadificación de la enfermedad, así como el diagnóstico molecular, resulta de vital importancia para valorar el pronóstico y adoptar la actitud terapéutica adecuada.

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