Nódulo tiroideo en el niño

  1. Martín-Alonso, Montserrat 1
  2. Prieto Matos, Pablo
  3. Bajo Delgado, Ana Fe 2
  4. Mories Álvarez, María Teresa 3
  5. Sánchez Marcos, Ana Isabel 3
  6. Pardal Refoyo, José Luis 4
  1. 1 Servicio de Pediatría. Complejo Asistencial Universitario de Salamanca
  2. 2 Hospital Universitario Salamanca, Servicio de Pediatría. Endocrinología Infantil
  3. 3 Hospital Universitario Salamanca, Servicio de Endocrinología
  4. 4 Hospital Universitario de Salamanca, Servicio de Otorrinolaringología
Aldizkaria:
Revista ORL

ISSN: 2444-7986 2444-7986

Argitalpen urtea: 2021

Alea: 12

Alea: 4

Orrialdeak: 353-358

Mota: Artikulua

DOI: 10.14201/ORL.25056 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

Beste argitalpen batzuk: Revista ORL

Laburpena

Introduction and objective: Thyroid nodules in children are rare (2% of children have palpable thyroid nodules and 5% of children have thyroid nodules by ultrasonography). Most of these are benign and asymptomatic, but the percentage of nodules harboring cancer in children is higher than in adults: the rate of malignancy varies from 10 to 50% depending on published case series. For this reason, it is very important evaluating and monitoring the thyroid nodules in children. Synthesis: The thyroid gland in children is more susceptible to certain carcinogenic agents than the thyroid gland in adults. Thus, clinical following of the thyroid nodules in children is very important. The American Thyroid Association (ATA) recognized that size criterion for performing fine-needle aspiration (FNA) in adults may not be appropriate in a growing thyroid gland in children. For this reason, the ATA recommended that ultrasound characterization and clinical context should be used in the evaluation. Benign thyroid nodules must be monitored by periodic neck palpation and ultrasound examinations, so that if a significant increase in size is detected, it may lead to consider repeating FNA or performing a surgical excision. Conclusions: Clinical and ultrasonographic monitoring in thyroid nodule in children is very important due to its higher rate of malignancy than in adults.

Erreferentzia bibliografikoak

  • Rallison ML, Dobyns BM, Keating FR Jr, et al. Thyroid nodularity in children. JAMA. 1975; 233:1069-1072.
  • Dimachkieh A, Kazahaya K, Chelius D. Assessment and management of thyroid disease in children. Otolaryngol Clin N Am. 2019;532:957-967.
  • Gharib H, Papini E, Garber J, et al. American Association of clinical Endocrinologists, American College of Endocrinology and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules. Update Endocrine Practice. 2016;22(1):1-60.
  • Salazar Campos N, Calderón Gómez MJ, Arias Vargas R. Abordaje del nódulo tiroideo en pediatría. Revista Médica Sinergia. 2020;5(8):e472.
  • Rallison ML, Dobyns BM, Meikle AW, et al. Natural history of thyroid abnormalities: prevalence, incidence, and regression of thyroid diseases in adolescents and young adults. Am J Med. 1991;91:363-370.
  • Kaloumenou I, Alevizaki M, Ladopoulus C, et al. Thyroid volumen and echostructure in schoolchildren living in an iodine-replete area: relation to age, pubertal stage and body mass index. Thyroid. 2007;17:875-881.
  • Stephen LaFranchi MD. Thyroid nodules and cancer in children. Post TW, ed. UpToDate. Walthan, MA: UpToDate Inc. https:\\www.uptodate.com (Accessed on August 13, 2020).
  • Niedziela M, Breborowicz D, Trejster E, et al. Hot nodules in children and adolescents in western Poland from 1996 to 2000: clinical analysis of 31 patients. J Pediatr Endocrinol Metab. 2002;15:823-830.
  • Ly S, Frates MC, Benson CB, et al. Features and outcome of autonomous thyroid nodules in children: 31 consecutive patients seen at a single center. J Clin Endocrinol Metab. 2016;101:3856-3862.
  • Neha K MD, Asha S MD, Edward YL MD. Practical indication based pediatric nuclear medicine studies. Radiol Clin N Am. 2017;55:803-844.
  • Horvath E, Majlis S, Rossi R, et al. An ultrasonogram reporting system for thyroid nodules stratifying risk for clinical management. J Clin Endocrinol Metab. 2009;94:1748-1751.
  • Francis GL, Waguespack SG, Bauer AJ, et al. Management guidelines for children with thyroid nodules and differentiated thyroid cancer. Thyroid. 2015;25:716-759.
  • Tessler F, Middleton W, Grant E. Thyroid Imaging Reporting and Data System (TIRADS): a user´s guide. Radiology. 2018;287(1):29-36.
  • Zabala RM, Korta I, Del Cura JL. Intervencionismo en el cuello. Radiología. 2016;58(s2):2-14.
  • Detweiler K, Elfenbein D, Mayers D. Evaluation of thyroid nodules. Surg Clin N Am. 2019;99:571-586.
  • Hodax JK, Bowerman K, Quintos JB. Benign thyroid nodules in pediatric patients: determining best practices for repeat ultrasound evaluations. J Pediatr Endocrinol Metab. 2019;32(8):895-901.
  • Cherella CE, Feldman HA, Hollowell M, et al. Natural history and outcomes of citologically benign thyroid nodules in children. J Pediatr Endocrinol Metab. 2018;103:3557-3565.
  • Ajmal S, Rapport S, Ramirez H, Mazzaglia P. The natural history of the benign thyroid nodule: What is the appropiate follow-up strategy?. J Am Coll Surg. 2015;978-992.
  • Hong H, Lee E, Jeong S, et al. Ultrasonography of various thyroid diseases in children and adolescents: a pictorial essay. Korean J Radiol. 2015;16(2):419-429.
  • Kamran SC, Marquesse E, Kim MI, et al. Thyroid nodule size and prediction of cancer. J Pediatr Endocrinol Metab. 2013;98(2):564-570.