Cáncer de tiroides en pediatría

  1. Prieto-Matos, Pablo
  2. Martín-Hernández, Diana 1
  3. Martín-Alonso, Montserrat
  4. Bajo-Delgado, Ana Fe
  5. Riesco-Riesco, Susana 2
  6. Prieto-Matos, Carlos
  1. 1 Unidad de Radiología; Hospital Universitario de Salamanca
  2. 2 Unidad de Onco-hematología Pediátrica; Hospital Universitario de Salamanca
Revista:
Revista ORL

ISSN: 2444-7986,  2444-7986

Any de publicació: 2021

Volum: 12

Volum: 4

Pàgines: 303-312

Tipus: Article

DOI: 10.14201/ORL.25061 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

Altres publicacions en: Revista ORL

Resum

Thyroid cancer is a rare disease in pediatric age; however it is increasing in the last few years, mainly in adolescent women. Although children and adult thyroid cancer are similar, they have some particular differences. The aim of this report is to analyze those differences, emphasizing the particularities of thyroid cáncer in pediatric age. The development of molecular genetic testing has allowed a deeper understanding of genetic predisposition síndromes, such as MEN2A, which has led to a significant increase in prophylactic thyroidectomies. The most frequent histological group is differentiated cáncer, specifically papilar type. At the time of diagnosis in children thyroid cancer presents a greater size and extensión, and more probabilities of multifocality and metastasis than in adults. The short-term prognosis is excellent; however in the long-term there are a significant number of recurrences and second tumors. It is important to carry out a personalized medicine, and to create diagnostic protocols. A Deep tumor characterization and the prognosis stratification will be essential to choose the correct treatment for each case, also to achieve maximum effectiveness, survival and to minimize side effects.

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Fuente de los datos: Dialnet