Uterine artery embolization for the treatment of uterine fibroids

  1. Ángel García-Iglesias 1
  2. Santiago González Perez 1
  3. David Beltrán Vaquero 2
  4. María de la O Rodríguez Martin 1
  5. Silvia García Valle
  6. José Luis Pérez Escanilla 1
  7. María José Doyague Sánchez 1
  8. Jesús García Alonso 1
  9. Luis Velasco Pelayo 1
  10. Josefina Basabe Picaso 1
  1. 1 Universitary Hospital of Salamanca
  2. 2 Institute of Public Health of Madrid.
Zeitschrift:
Revista Electrónica de Biomedicina

ISSN: 1697-090X

Datum der Publikation: 2013

Nummer: 1

Seiten: 9-17

Art: Artikel

DIALNET GOOGLE SCHOLAR lock_openOpen Access editor

Andere Publikationen in: Revista Electrónica de Biomedicina

Zusammenfassung

AIM: To determine the outcome of uterine artery embolization in patients with symptomatic uterine fibroids, in order to assess the response of symptoms and fibroid size. METHODS: We analyzed the results of a population study of 112 patients with uterine fibroids made in the period between 2006 and 2010. Main parameters were assessed improvement or disappearance of symptoms and downsizing the adverse effects of the procedure. RESULTS: The predominant age of the patients are in the group of 41-45 years with 80.35%, being the most common symptom of menorrhagia 66.07%, myoma volume ranged between 35cm3 and 523cm3, and procedure duration ranged from 1 hour to 2.5 hours. The most common symptoms after embolization was mild pain 44.64%, not having symptoms in 43.75%. Also it was associated nausea in 8.03% and vomiting in 3.57% as other adverse effects. After three months of treatment 47.32% had oligomenorrhea and amenorrhea was 17.85%. Fibroid size at 6 months was reduced significantly dominate the volume between 36 and 113cm3. CONCLUSION: Uterine artery embolization is an effective treatment for symptomatic fibroids, considered an alternative to surgical treatment.

Bibliographische Referenzen

  • Aubuchon M. Pinto A. Wilians DB. Treatment of uterine fibroids. Obstet Gynecol. 2002;9(6):231-237.
  • -Dutton S. Hirst A, McPherson K, Nicholson T, Maresh M. A UK multicentre retrospective cohort study comparing hysterectomy and uterine artery embolisatiom for the treatment of syntomatic uterine fibroids (HOPEFUL study) main results on medium-term safety and efficacy. BJOG 2007;114 (3):1340-1351.
  • Helal A, Mashaly A, Amer T. Uterine artery occlusion for treatment of symptomatic uterine myomas. JSLS 2010;14 (2)386-390.
  • Volkers NA, Herenkampt WJ, Birnie E, De Vries C, Holt C, Ankun WM et al. Uterine artery embolization in the treatment of symptomatic uterine fibroid tumors: periprocedural results and complications. JVIR 2006;17 (3):471-480.
  • Ravina JH, Herbreteau D, Ciraru-Vigrneron N, Bouret JM, Houdart E, Aymard A, et al. Arterial embolization to treat uterine myomata. Lancet 1995; 346(4W):671-672.
  • Goodwin SC, Vedantham S, McLucas B, Forno AE, Perella R. Preliminary experience with uterine artery embolization for uterine fibroids. JVR 1997;8 (5):517526.
  • Stovall DW. Alternatives to hysterectomy focus on global endometrial ablation uterine fibroid embolization and magnetic resonance-guided focused ultrasound. Menopause 2011,18 (4):437-444.
  • Bihim T, Pisco JM, Duarte M, Oliveira AG. Polyvinyl alcohol particle size for uterine artery embolization: a prospective randomized study of initial use of 350-500 um particles. J Vas Interv Radiol 2011; 22(1):21-27.
  • Lohle PN, De Vries J, Klazen CA, Boekkooi PF, Vervest HA, et al. Uterine artery embolization for symptomatic adenomyosis with or without uterine leiomyomas with the use of calibrated tris-acryl gelatin microspheres: midterm clinical and MR imaging follow-up. J Vasc Interv Radiol 2007; 18 (7):835-841.
  • Sone M, Aral Y, Shimizu T, Takeuchi Y, Higashihara H, Ohgi S. Et At. Phase I/II multiinstitutional study of uterine artery embolization with gelatin sponge for syntomatic uterine leiomyomata: Japan intervional radiology in oncology study group study. J Vasc Interv Radiol 2010; 21(11):1665-1670.
  • Smith SJ. Embolization leiomyoma uterine. Am Fam Physician 2000; 61 (7):3601-3611.
  • Nasser F, Alfonso BB, de Jesus SG, Coelho D, Ziotnik E, Messina MD. et al. Uterine fibroid embolization in women with giant fibroids. Rev Bras Ginecol Obstet. 2010; 32 (11):530-535.
  • Mukhamed'ianov IF, Fedorov SV. Clinical aspects of uterine embolization efficacy in uterine myomas. Angiol Sosud Khir 2010; 16 (2):43-46.
  • Spies JB, Bradley LD, Guido R, Maxwell GL, Levine BA, Coyne K. Outcomes from leiomoma therapies: comparison with normal control. Obstet Gynecol 2010;116(3):641-652.
  • Miljailovic MZ, Lukic SM, Jankovic SM, Surlan K. Arterial embolization of uterine fibroids. J Buon 2010;15(4):704- 707.
  • Scheuring-Muernkler C, Wagner M, Franiel T, Hamm B, Kroencke TJ. Effect of uterine artery embolization on uterine and leiomyoma perfusion: evidence of transient myometrial ischemia on magnetic resonance imaging. J Vasc Interv Radiol. 2010;21(9):1347-1353.
  • Rajan DK, Margau R, Kroll RR,Simons ME, Tan KT, Jaskolka JD. Et Al: Clinical utility of ultrasound versus magnetic resonance imaging for deciding to proceed with uterine artery embolization for presumed symtomatic fibroids. Clin Radiol 2011;66(1):57-62.
  • Vykliulk MV, Dedy TV: Ultrasound characteristics of uterine myoma before and after uterine artery embolization. Vestn Rentgenol Radiol. 2011; 36 (1): 18-21.
  • Van der Kooij SM, Hehenkamp WJ, Volkers NA,Birnie E, Ankum WM,Reekers JA. Uterine artery embolization vs hysterectomy in the treatment of symtomatic uterine fibroids 5-year outcome from the randomized EMMY trial. Am J Obst Gynecol 2010;203(2):105-10.
  • Txier H, Grevoul J, Loffroy R, et al. Uterine arteries in preparation for consecutive uterine fibroma surgery. Act Obtet Gynecol Scand. 2010;89(10):1310-1315.
  • Hu NN, Kaw D, McCullough MF, Nsouli H,Spies JB: Menopause and menopausal symptoms after ovarian artery embolization: a comparison with uterine artery embolization controls. J Vas Interv Radiol 2010;22(5):710-715.
  • Kim KA, Yoon SW, Yoon BS, Park CT, Kim SH, Lee JT: Spontaneous vaginal expulsion of uterine mioma after Magnetic resonance-guided focoused ultrasound surgery. J Minin Invasive Gynecol 2011;18(1):131-134.
  • Ahn EH, Mastsuo K. Area of uncertainty in uterine arterial embolization does it increase the risk of ovarian cancer. J Obstet Gynaecol Res 2010;36(4):920.
  • Goldberg J. Advanced ovarian carcinoma following bilateral uterine embolization. J Reprod Med 2010;55(3):179- 180
  • Pinto I, Porras J, Ayerbe E, Millan I, Bruna I, Cano ML. Pregnancy after uterine fibroid embolization: follow-up of 100 patients using tris-acryl gelatin microspheres. Fertil and Steril 2008;90(6):2356-2360
  • Takahashi H, Hayashi S, Matsuoka K, Kitagawa M. Placenta accreta following uterine artery embolization. Taiwan J Obstet Gynecol 2010;49(2):197-198
Fuente de los datos: Dialnet