Avances en el desarrollo de nuevas vacunas contra Fasciola hepatica

  1. Perallón Mantas, Darío 1
  2. Sánchez Montejo, Javier 1
  3. Muro Álvarez, Antonio
  1. 1 Grupo de Enfermedades Infecciosas y Tropicales (e-INTRO). Instituto de Investigaciones Biomédicas de Salamanca-Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca (IBSAL-CIETUS). Facultad de Farmacia. Universidad de Salamanca
Zeitschrift:
Farmajournal

ISSN: 2445-1355

Datum der Publikation: 2023

Ausgabe: 8

Nummer: 1

Seiten: 49-57

Art: Artikel

DOI: 10.14201/FJ2023814957 DIALNET GOOGLE SCHOLAR lock_openOpen Access editor

Andere Publikationen in: Farmajournal

Zusammenfassung

Fasciolosis is a zoonosis caused by the trematode Fasciola hepatica that widely affects the livestock sector. However, an effective vaccine has not yet been developed to prevent the spread of this parasite. In this work, messenger ribonucleic acid technology has been used to develop a transcript of a recombinant protein of Fasciola hepatica that can be used to complete the formulation of a possible vaccine. Thanks to the use of plasmids as cloning vectors of the sequence of our antigenic protein of interest, in the study we will transform this protein into bacterial cultures for later transcription

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