Repercusión de vortioxetina sobre la función sexual frente a otros antidepresivos(Pag.-e 101997)

  1. F. Sánchez-Sánchez 1
  2. B. Ponce-Buj 2
  3. A.L. Montejo-González 3
  4. Y. Sipán-Sarrión 1
  5. A. Gimeno-Marqués 4
  6. A. Merino-Gámez 5
  1. 1 Centro de Salud Xàtiva, Xàtiva, Valencia, España
  2. 2 Centro de Salud Alaquàs, Alaquàs, Valencia, España
  3. 3 Clínico Universitario de Salamanca, Salamanca, España
  4. 4 Centro de Salud L’Alcúdia, L’Alcúdia, Valencia, España
  5. 5 Centro de Salud Rafelbunyol, Rafelbunyol, Valencia, España
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Revista:
Semergen: revista española de medicina de familia

ISSN: 1138-3593

Any de publicació: 2023

Número: 7

Pàgines: 2-2

Tipus: Article

DOI: 10.1016/J.SEMERG.2023.101997 DIALNET GOOGLE SCHOLAR

Altres publicacions en: Semergen: revista española de medicina de familia

Resum

Objective To analyze the impact of the antidepressant vortioxetine on sexual function, compared to selective serotonin reuptake inhibitors (SSRIs) and mixed selective serotonin and norepinephrine reuptake inhibitors (IRSN or Dual) in patients with depression. Material and methods Analytical, observational, longitudinal and prospective study, which included men and women over 18 years of age, with depressive disorder and sexual activity with a partner, separating them into two groups: (i) study, starting treatment with vortioxetine; (2) control, maintaining treatment with SSRIs or Duals. Three visits were made: inclusion, follow-up at 4 weeks and final 3 months from inclusion. The total follow-up period was 3 months. Results A total of 87 patients were included (mean age 46.85 years). At the end of the study, significant differences (SD) were found in the mean value of the sum of the scores of the evaluative domains of the sexual response of the Women's Sexual Function Questionnaire (FSM-2) between the study group and the control (22.42 ± 4.39 and 16.13 ± 7.76, respectively), with a lower risk of sexual dysfunction in women treated with vortioxetine. Also, lower risk of sexual dysfunction in these same women in the domains of desire, lubrication, orgasm, sexual frequency and sexual satisfaction. These differences were not found when assessing male sexual function. Conclusions Women treated with vortioxetine presented better sexual function than those treated with SSRIs or Duals and a lower risk of sexual dysfunction.

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Fuente de los datos: Dialnet