BIOLOGÍA MOLECULAR Y PATOGÉNESIS FÚNGICA
Publikationen (24) Publikationen, an denen Forscher/innen teilgenommen haben
2023
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
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Proteomic dissection of the role of GliZ in gliotoxin biosynthesis in Aspergillus fumigatus
Fungal Genetics and Biology, Vol. 166
2022
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A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
Cell Reports, Vol. 38, Núm. 11
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Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model
Molecular Oncology, Vol. 16, Núm. 19, pp. 3533-3553
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Expression of the K74 Killer Toxin from Saccharomyces paradoxus Is Modulated by the Toxin-Encoding M74 Double- Stranded RNA 59 Untranslated Terminal Region
Applied and Environmental Microbiology, Vol. 88, Núm. 8
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Hematopoietic Cells Influence Vascular Development in the Retina
Cells, Vol. 11, Núm. 20
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Regulation of zinc homeostatic genes by environmental pH in the filamentous fungus Aspergillus fumigatus
Environmental Microbiology, Vol. 24, Núm. 2, pp. 643-666
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The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function
Oncogene, Vol. 41, Núm. 24, pp. 3341-3354
2021
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At the metal–metabolite interface in aspergillus fumigatus: Towards untangling the intersecting roles of zinc and gliotoxin
Microbiology (United Kingdom), Vol. 167, Núm. 11
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Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis
EMBO Journal, Vol. 40, Núm. 22
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Distinct roles of vav family members in adaptive and innate immune models of arthritis
Biomedicines, Vol. 9, Núm. 6
2020
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VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma
Nature Communications, Vol. 11, Núm. 1
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Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis
Nature Communications, Vol. 11, Núm. 1
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Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor
Oncogene, Vol. 39, Núm. 28, pp. 5098-5111
2019
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Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, Particularly Aspergillus spp.: Molecular and Therapeutic Implications
Frontiers in Microbiology, Vol. 10
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Special issue: Fungal pathogenesis in humans: The growing threat
Genes
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The interplay between zinc and iron homeostasis in Aspergillus fumigatus under zinc-replete conditions relies on the iron-mediated regulation of alternative transcription units of zafA and the basal amount of the ZafA zinc-responsiveness transcription factor
Environmental Microbiology, Vol. 21, Núm. 8, pp. 2787-2808
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Vagal afferents contribute to sympathoexcitation-driven metabolic dysfunctions
Journal of Endocrinology, Vol. 240, Núm. 3, pp. 483-496
2018
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A novel polyaminocarboxylate compound to treat murine pulmonary aspergillosis by interfering with zinc metabolism
Antimicrobial Agents and Chemotherapy, Vol. 62, Núm. 6
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Novel zinc-attenuating compounds as potent broad-spectrum antifungal agents with in vitro and in vivo efficacy
Antimicrobial Agents and Chemotherapy, Vol. 62, Núm. 5