SEÑALIZACIÓN, DIVISIÓN Y CRECIMIENTO CELULAR
Publikationen (44) Publikationen, an denen Forscher/innen teilgenommen haben
2024
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Generation of Meiotic Mouse Models Using CRISPR/Cas9 Technology
Methods in molecular biology (Clifton, N.J.), Vol. 2818, pp. 93-112
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RNF212B E3 ligase is essential for crossover designation and maturation during male and female meiosis in the mouse
Proceedings of the National Academy of Sciences of the United States of America, Vol. 121, Núm. 25
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VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma
Scientific Reports, Vol. 14, Núm. 1
2023
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
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Synaptonemal Complex in Human Biology and Disease
Cells, Vol. 12, Núm. 13
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The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
Cancer research, Vol. 83, Núm. 2, pp. 239-250
2022
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A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
Cell Reports, Vol. 38, Núm. 11
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A truncating variant of RAD51B associated with primary ovarian insufficiency provides insights into its meiotic and somatic functions
Cell Death and Differentiation, Vol. 29, Núm. 12, pp. 2347-2361
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Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model
Molecular Oncology, Vol. 16, Núm. 19, pp. 3533-3553
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Identification of Germinal Neurofibromin Hotspots
Biomedicines, Vol. 10, Núm. 8
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The Oocyte-Specific Linker Histone H1FOO Is Not Essential for Mouse Oogenesis and Fertility
Cells, Vol. 11, Núm. 22
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The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function
Oncogene, Vol. 41, Núm. 24, pp. 3341-3354
2021
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Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis
EMBO Journal, Vol. 40, Núm. 22
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Dictyostelium discoideum as a non-mammalian biomedical model
Microbial Biotechnology, Vol. 14, Núm. 1, pp. 111-125
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Distinct roles of vav family members in adaptive and innate immune models of arthritis
Biomedicines, Vol. 9, Núm. 6
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Efficient fractionation and analysis of ribosome assembly intermediates in human cells
RNA Biology, Vol. 18, Núm. S1, pp. 182-197
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Integrated in silico MS-based phosphoproteomics and network enrichment analysis of RASopathy proteins
Orphanet Journal of Rare Diseases, Vol. 16, Núm. 1
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NAMPT-derived NAD+fuels PARP1 to promote skin inflammation through parthanatos cell death
PLoS Biology, Vol. 19, Núm. 11
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New functions of vav family proteins in cardiovascular biology, skeletal muscle, and the nervous system
Biology, Vol. 10, Núm. 9
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Vav proteins as double agents in cancer: Oncogenes with tumor suppressor roles
Biology, Vol. 10, Núm. 9