MECANISMOS DE SEÑALIZACIÓN EN ENFERMEDADES CARDIOVASCULARES Y OTRAS PATOLOGÍAS: DE LA INVESTIGACIÓN BÁSICA A LA CLÍNICA
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Instituto de Investigación Sanitaria La Fe
Valencia, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Investigación Sanitaria La Fe (11)
2024
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ADAMTS13 recovery in acute thrombotic thrombocytopenic purpura after caplacizumab therapy
Blood, Vol. 143, Núm. 18, pp. 1807-1815
2021
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A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis
American Journal of Hematology
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C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells
Cell Death and Disease, Vol. 12, Núm. 4
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C3G protein, a new player in glioblastoma
International Journal of Molecular Sciences, Vol. 22, Núm. 18
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Contribution of c3g and other gefs to liver cancer development and progression
Hepatoma Research, Vol. 7
2020
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C3G contributes to platelet activation and aggregation by regulating major signaling pathways
Signal Transduction and Targeted Therapy, Vol. 5, Núm. 1
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C3G is upregulated in hepatocarcinoma, contributing to tumor growth and progression and to HGF/MET pathway activation
Cancers, Vol. 12, Núm. 8, pp. 1-22
2019
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Identification of 58 mutations (26 Novel) in 94 of 109 symptomatic Spanish probands with protein C deficiency
Thrombosis and Haemostasis, Vol. 119, Núm. 9, pp. 1409-1418
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Involvement of antifactor VIII autoantibodies specificity in the outcome of inhibitor eradication therapies in acquired hemophilia a patients
Blood Coagulation and Fibrinolysis, Vol. 30, Núm. 3, pp. 127-132
2016
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C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
Oncotarget, Vol. 7, Núm. 29, pp. 45060-45078
2012
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C3G transgenic mouse models with specific expression in platelets reveal a new role for C3G in platelet clotting through its GEF activity
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1823, Núm. 8, pp. 1366-1377