Publicaciones en colaboración con investigadores/as de Instituto de Biología Molecular y Celular del Cáncer de Salamanca / Centro de Investigación del Cáncer (19)

2023

  1. GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina

    Cells, Vol. 12, Núm. 21

2021

  1. Ras GEF Mouse Models for the Analysis of Ras Biology and Signaling

    Methods in Molecular Biology (Humana Press Inc.), pp. 361-395

2019

  1. A Nucleotide-Dependent Conformational Switch Controls the Polymerization of Human IMP Dehydrogenases to Modulate their Catalytic Activity

    Journal of Molecular Biology, Vol. 431, Núm. 5, pp. 956-969

  2. Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice

    Cell Death and Disease, Vol. 10, Núm. 11

  3. Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses

    Journal of Leukocyte Biology, Vol. 106, Núm. 4, pp. 815-822

2018

  1. Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis

    Leukemia, Vol. 32, Núm. 3, pp. 820-827

  2. The RAS-ERK pathway: A route for couples

    Science Signaling, Vol. 11, Núm. 554

2017

  1. A new functional role uncovered for RASGRF2 in control of nuclear migration in cone photoreceptors during postnatal retinal development

    Small GTPases

  2. Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus

    Molecular and Cellular Neuroscience, Vol. 85, pp. 127-147

2015

  1. Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

    European Journal of Pharmaceutics and Biopharmaceutics, Vol. 93, pp. 52-79

  2. CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium

    Scientific Reports, Vol. 5

2012

  1. The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development

    Molecular Biology of the Cell, Vol. 23, Núm. 12, pp. 2373-2387

2010

  1. Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice

    Kidney International, Vol. 77, Núm. 6, pp. 509-518

  2. Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

    EMBO Journal, Vol. 29, Núm. 6, pp. 1091-1104

2009

  1. Differential involvement of H- and K-Ras in Raf-1 activation determines the role of calmodulin in MAPK signaling

    Cellular Signalling, Vol. 21, Núm. 12, pp. 1827-1836

  2. Targeted genomic disruption of H-ras and N-ras has no effect on early renal changes after unilateral ureteral ligation

    World Journal of Urology, Vol. 27, Núm. 6, pp. 787-797

2007

  1. p73 cooperates with Ras in the activation of MAP kinase signaling cascade

    Cell Death and Differentiation, Vol. 14, Núm. 2, pp. 254-265

2006

  1. Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl

    Experimental Cell Research, Vol. 312, Núm. 6, pp. 938-948

2004

  1. C3G-mediated suppression of oncogene-induced focus formation in fibroblasts involves inhibition of ERK activation, cyclin a expression and alterations of anchorage-independent growth

    Oncogene, Vol. 23, Núm. 28, pp. 4885-4893