GTPASAS Y CÁNCER: SEÑALIZACIÓN MEDIADA POR RAS
Publicaciones (37) Publicaciones en las que ha participado algún/a investigador/a
2023
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Advances in Molecular Research of Oncogenes
International Journal of Molecular Sciences
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
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Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma
Nature Communications, Vol. 14, Núm. 1
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GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina
Cells, Vol. 12, Núm. 21
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Optimized Protocol for Isolation and Culture of Murine Neonatal Primary Lung Fibroblasts
Methods and Protocols, Vol. 6, Núm. 1
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PKD phosphorylation and COP9/Signalosome modulate intracellular Spry2 protein stability
Oncogenesis, Vol. 12, Núm. 1
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Unveiling the Mysteries of RAS Signaling: A Journey of Discovery and Breakthroughs
Genes
2022
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Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia
Cancers, Vol. 14, Núm. 16
2021
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40 years of RAS-a historic overview
Genes, Vol. 12, Núm. 5
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Anthraquinones as inhibitors of SOS RAS-GEF activity
Biomolecules, Vol. 11, Núm. 8
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Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis
Oncogene, Vol. 40, Núm. 27, pp. 4538-4551
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Functional specificity of the members of the sos family of ras‐gef activators: Novel role of sos2 in control of epidermal stem cell homeostasis
Cancers, Vol. 13, Núm. 9
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Ras GEF Mouse Models for the Analysis of Ras Biology and Signaling
Methods in Molecular Biology (Humana Press Inc.), pp. 361-395
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Sos2 comes to the fore: Differential functionalities in physiology and pathology
International Journal of Molecular Sciences, Vol. 22, Núm. 12
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The Crossroads between RAS and RHO Signaling Pathways in Cellular Transformation, Motility and Contraction
Genes, Vol. 12, Núm. 6
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The childhood-onset neurodegeneration with cerebellar atrophy (Condca) disease caused by agtpbp1 gene mutations: The purkinje cell degeneration mouse as an animal model for the study of this human disease
Biomedicines, Vol. 9, Núm. 9
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The importance of being PI3K in the RAS signaling network
Genes, Vol. 12, Núm. 7
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The reversed intra- and extracellular pH in tumors as a unified strategy to chemotherapeutic delivery using targeted nanocarriers
Acta Pharmaceutica Sinica B, Vol. 11, Núm. 8, pp. 2243-2264
2020
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SOS GEFs in health and disease
Biochimica et Biophysica Acta - Reviews on Cancer, Vol. 1874, Núm. 2
2019
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A Nucleotide-Dependent Conformational Switch Controls the Polymerization of Human IMP Dehydrogenases to Modulate their Catalytic Activity
Journal of Molecular Biology, Vol. 431, Núm. 5, pp. 956-969