Publicacións (24) Publicacións de IGNACIO GARCÍA-TUÑÓN LLANIO

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2025

  1. Examining the Effects of the RUNX1 p.Leu43Ser Variant on FPD/AML Phenotypes Using a CRISPR/Cas9-Generated Knock-In Murine Model

    Biomolecules, Vol. 15, Núm. 5

2024

  1. Histone Acetyl Transferase 1 Is Overexpressed in Poor Prognosis, High-grade Meningeal and Glial Brain Cancers: Immunohistochemical and Aptahistochemical Study

    Journal of Histochemistry and Cytochemistry, Vol. 72, Núm. 8-9, pp. 585-599

2023

  1. A Potential Effect of Circadian Rhythm in the Delivery/Therapeutic Performance of Paclitaxel–Dendrimer Nanosystems

    Journal of Functional Biomaterials, Vol. 14, Núm. 7

  2. Chronic Venous Disease during Pregnancy Is Related to Inflammation of the Umbilical Cord: Role of Allograft Inflammatory Factor 1 (AIF-1) and Interleukins 10 (IL-10), IL-12 and IL-18

    Journal of Personalized Medicine, Vol. 13, Núm. 6

  3. METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer

    Molecular cancer, Vol. 22, Núm. 1, pp. 119

  4. Novel variants in GALE cause syndromic macrothrombocytopenia by disrupting glycosylation and thrombopoiesis

    Blood, Vol. 141, Núm. 4, pp. 406-421

  5. Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease

    Genes, Vol. 14, Núm. 4

2022

  1. A novel nonsense variant in TPM4 caused dominant macrothrombocytopenia, mild bleeding tendency and disrupted cytoskeleton remodeling

    Journal of Thrombosis and Haemostasis, Vol. 20, Núm. 5, pp. 1248-1255

  2. CRISPR/Cas9‐Directed Gene Trap Constitutes a Selection System for Corrected BCR/ABL Leukemic Cells in CML

    International Journal of Molecular Sciences, Vol. 23, Núm. 12

2021

  1. Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression

    Blood Cancer Journal, Vol. 11, Núm. 7

  2. CRISPR-Cas9 Technology as a Tool to Target Gene Drivers in Cancer: Proof of Concept and New Opportunities to Treat Chronic Myeloid Leukemia

    CRISPR Journal, Vol. 4, Núm. 4, pp. 519-535

  3. Characterization of the platelet phenotype caused by a germline RUNX1 Variant in a CRISPR/Cas9-generated murine model

    Thrombosis and Haemostasis, Vol. 121, Núm. 9, pp. 1193-1205

  4. Cyba-deficient mice display an increase in hematopoietic stem cells and an overproduction of immunoglobulins

    Haematologica, Vol. 106, Núm. 1, pp. 142-153

  5. Future approaches for treating chronic myeloid leukemia: Crispr therapy

    Biology, Vol. 10, Núm. 2, pp. 1-16

  6. Granuloma formation in a cyba-deficient model of chronic granulomatous disease is associated with myeloid hyperplasia and the exhaustion of B-cell lineage

    International Journal of Molecular Sciences, Vol. 22, Núm. 16

  7. Loss of HDAC11 accelerates skeletal muscle regeneration in mice

    FEBS Journal, Vol. 288, Núm. 4, pp. 1201-1223

  8. Priming human adipose-derived mesenchymal stem cells for corneal surface regeneration

    Journal of Cellular and Molecular Medicine, Vol. 25, Núm. 11, pp. 5124-5137

2020

  1. CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition

    Leukemia, Vol. 34, Núm. 6, pp. 1599-1612

  2. ETV6/RUNX1 Fusion Gene Abrogation Decreases the Oncogenicity of Tumour Cells in a Preclinical Model of Acute Lymphoblastic Leukaemia

    Cells, Vol. 9, Núm. 1

  3. Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology

    Molecular Biology Reports, Vol. 47, Núm. 2, pp. 1381-1391