
Rubén
Deogracias Pastor
Personal Docente, Investigador o Técnico
Publications (17) Rubén Deogracias Pastor publications
2024
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Neurotrophins and Their Receptors: BDNF’s Role in GABAergic Neurodevelopment and Disease
International Journal of Molecular Sciences, Vol. 25, Núm. 15
2023
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Enhanced TrkA signaling impairs basal forebrain-dependent behavior
Frontiers in Molecular Neuroscience, Vol. 16
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Mechanisms Controlling the Expression and Secretion of BDNF
Biomolecules, Vol. 13, Núm. 5
2022
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Origin, Development, and Synaptogenesis of Cortical Interneurons
Frontiers in Neuroscience, Vol. 16
2020
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TrkB deubiquitylation by USP8 regulates receptor levels and BDNF-dependent neuronal differentiation
Journal of Cell Science, Vol. 133, Núm. 24
2019
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Neurodevelopment: Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits
Science, Vol. 363, Núm. 6425, pp. 413-417
2018
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The Microtubule Regulator NEK7 Coordinates the Wiring of Cortical Parvalbumin Interneurons
Cell Reports, Vol. 24, Núm. 5, pp. 1231-1242
2017
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Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican
Neuron, Vol. 95, Núm. 3, pp. 639-655.e10
2012
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BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons
Journal of Cell Biology, Vol. 196, Núm. 6, pp. 775-788
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Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons
Stem Cells, Vol. 30, Núm. 10, pp. 2128-2139
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Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome
Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 35, pp. 14230-14235
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Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity
Cell Death and Disease, Vol. 3, Núm. 1
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Seizure-induced neuronal death is suppressed in the absence of the endogenous lectin galectin-1
Journal of Neuroscience, Vol. 32, Núm. 44, pp. 15590-15600
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Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state
Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 16
2010
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Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth
Journal of Neuroscience, Vol. 30, Núm. 5, pp. 1739-1749
2005
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Transcription of the NR1 subunit of the N-methyl-D-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia
Journal of Biological Chemistry, Vol. 280, Núm. 41, pp. 35018-35027
2004
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Expression of the neurotrophin receptor trkB is regulated by the cAMP/CREB pathway in neurons
Molecular and Cellular Neuroscience, Vol. 26, Núm. 3, pp. 470-480