José María
Medina Jiménez
Profesor Emérito Honorífico
Instituto de Neurociencias de Castilla y León
Salamanca, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Neurociencias de Castilla y León (31)
2020
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Connexin43 peptide, TAT-Cx43266-283, selectively targets glioma cells, impairs malignant growth, and enhances survival in mouse models in vivo
Neuro-Oncology, Vol. 22, Núm. 4, pp. 493-504
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Connexin43 region 266–283, via src inhibition, reduces neural progenitor cell proliferation promoted by egf and fgf-2 and increases astrocytic differentiation
International Journal of Molecular Sciences, Vol. 21, Núm. 22, pp. 1-22
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Targeting metabolic plasticity in glioma stem cells in vitro and in vivo through specific inhibition of c-Src by TAT-Cx43266-283
EBioMedicine, Vol. 62
2018
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Endocytosis and Transcytosis of Amyloid-β Peptides by Astrocytes: A Possible Mechanism for Amyloid-β Clearance in Alzheimer's Disease
Journal of Alzheimer's Disease, Vol. 65, Núm. 4, pp. 1109-1124
2017
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A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK
Stem Cell Reports, Vol. 9, Núm. 2, pp. 451-463
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A c-Src inhibitor peptide based on connexin43 exerts neuroprotective effects through the inhibition of glial hemichannel activity
Frontiers in Molecular Neuroscience, Vol. 10
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Biotinylated cell-penetrating peptides to study intracellular protein-protein interactions
Journal of Visualized Experiments, Vol. 2017, Núm. 130
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Restrained Phosphatidylcholine Synthesis in a Cellular Model of Down’s Syndrome is Associated with the Overexpression of Dyrk1A
Molecular Neurobiology, Vol. 54, Núm. 2, pp. 1092-1100
2016
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Aberrant co-localization of synaptic proteins promoted by Alzheimer's Disease amyloid-β peptides: Protective effect of human serum albumin
Journal of Alzheimer's Disease, Vol. 55, Núm. 1, pp. 171-182
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Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes
Oncotarget, Vol. 7, Núm. 31, pp. 49819-49833
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The role of connexin43-Src interaction in astrocytomas: A molecular puzzle
Neuroscience, Vol. 323, pp. 183-194
2015
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Alpha-fetoprotein (AFP) modulates the effect of serum albumin on brain development by restraining the neurotrophic effect of oleic acid
Brain Research, Vol. 1624, pp. 45-58
2014
2013
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Overexpression of DYRK1A inhibits choline acetyltransferase induction by oleic acid in cellular models of Down syndrome
Experimental Neurology, Vol. 239, Núm. 1, pp. 229-234
2012
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HIF-1 and c-Src mediate increased glucose uptake induced by endothelin-1 and connexin43 in astrocytes
PLoS ONE, Vol. 7, Núm. 2
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Reduced connexin43 expression correlates with c-Src activation, proliferation, and glucose uptake in reactive astrocytes after an excitotoxic insult
GLIA, Vol. 60, Núm. 12, pp. 2040-2049
2010
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Connexin43 inhibits the oncogenic activity of c-Src in C6 glioma cells
Oncogene, Vol. 29, Núm. 42, pp. 5712-5723
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Inhibition of ATP-sensitive potassium channels increases HSV-tk/GCV bystander effect in U373 human glioma cells by enhancing gap junctional intercellular communication
Neuropharmacology, Vol. 59, Núm. 6, pp. 480-491
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Oleic acid synthesized in the periventricular zone promotes axonogenesis in the striatum during brain development
Journal of Neurochemistry, Vol. 114, Núm. 6, pp. 1756-1766