XOSE R.
GARCIA BUSTELO
Investigador
Universidad Autónoma de Madrid
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Universidad Autónoma de Madrid (14)
2023
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An Optimized Single Nucleotide Polymorphism-Based Detection Method Suggests That Allelic Variants in the 3’ Untranslated Region of RRAS2 Correlate with Treatment Response in Chronic Lymphocytic Leukemia Patients
Cancers, Vol. 15, Núm. 3
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Characterization of Three Somatic Mutations in the 3′UTR of RRAS2 and Their Inverse Correlation with Lymphocytosis in Chronic Lymphocytic Leukemia
Cells, Vol. 12, Núm. 23
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
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Mice Overexpressing Wild-Type RRAS2 Are a Novel Model for Preclinical Testing of Anti-Chronic Lymphocytic Leukemia Therapies
Cancers, Vol. 15, Núm. 24
2022
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A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
Cell Reports, Vol. 38, Núm. 11
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Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia
Molecular Cancer, Vol. 21, Núm. 1
2018
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R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes
Science Signaling, Vol. 11, Núm. 532
2017
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A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia
Cancer Cell, Vol. 32, Núm. 5, pp. 608-623.e9
2014
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Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease
Nature Communications, Vol. 5
2013
2009
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Essential function for the GTPase TC21 in homeostatic antigen receptor signaling
Nature Immunology, Vol. 10, Núm. 8, pp. 880-888
2008
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Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling
Cellular Signalling, Vol. 20, Núm. 4, pp. 758-770
2004
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F-actin-dependent Translocation of the Rap1 GDP/GTP Exchange Factor RasGRP2
Journal of Biological Chemistry, Vol. 279, Núm. 19, pp. 20435-20446
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Signaling through the Leukocyte Integrin LFA-1 in T Cells Induces a Transient Activation of Rac-1 That Is Regulated by Vav and PI3K/Akt-1
Journal of Biological Chemistry, Vol. 279, Núm. 16, pp. 16194-16205