Publicaciones (15) Publicaciones de María Concepción Pérez Melero

2019

  1. Dihydropyrimidine-2-thiones as Eg5 inhibitors and L-type calcium channel blockers: Potential antitumour dual agents

    MedChemComm, Vol. 10, Núm. 9, pp. 1589-1598

2014

  1. KSP inhibitors as antimitotic agents

    Current Topics in Medicinal Chemistry, Vol. 14, Núm. 20, pp. 2286-2311

2011

  1. Synthesis of novel polynitrogenated drugs based on phenstatins. Tubulin polymerization evaluation

    4TH EUROPEAN CONFERENCE ON CHEMISTRY FOR LIFE SCIENCES

2010

  1. Exploring the effect of 2,3,4-trimethoxy-phenyl moiety as a component of indolephenstatins

    European Journal of Medicinal Chemistry, Vol. 45, Núm. 2, pp. 588-597

2008

  1. Diarylmethyloxime and hydrazone derivatives with 5-indolyl moieties as potent inhibitors of tubulin polymerization

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 11, pp. 5952-5961

  2. Naphthylphenstatins as tubulin ligands: Synthesis and biological evaluation

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 19, pp. 8999-9008

2007

  1. Conformationally restricted macrocyclic analogues of combretastatins

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 22, pp. 6316-6320

  2. Synthesis and biological activity of naphthalene analogues of phenstatins: Naphthylphenstatins

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 12, pp. 3417-3420

2005

  1. Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety

    Journal of Medicinal Chemistry, Vol. 48, Núm. 2, pp. 556-568

  2. New naphthylcombretastatins. Modifications on the ethylene bridge

    Bioorganic and Medicinal Chemistry, Vol. 13, Núm. 6, pp. 2097-2107

  3. Stilbenophane analogues of deoxycombretastatin A-4

    Journal of Organic Chemistry, Vol. 70, Núm. 16, pp. 6544-6547

  4. Studies on thiamine diphosphate-dependent enzymes

    Biochemical Society Transactions

  5. Synthesis of a conformationally restricted polyoxygenated crownophane

    Tetrahedron Letters, Vol. 46, Núm. 41, pp. 7055-7057

2004

  1. A new family of quinoline and quinoxaline analogues of combretastatins

    Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 14, pp. 3771-3774

  2. Naphthalene combretastatin analogues: Synthesis, cytotoxicity and antitubulin activity

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 19, Núm. 6, pp. 521-540