Emilio
Fernández Sánchez
Profesor Titular de Universidad
Publications (35) Emilio Fernández Sánchez publications
2024
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Weak neuronal glycolysis sustains cognition and organismal fitness
Nature Metabolism
2023
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Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognition
Nature Metabolism, Vol. 5, Núm. 8, pp. 1290-1302
2022
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Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis
Nature Communications, Vol. 13, Núm. 1
2019
2018
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NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program
Stem Cell Reports, Vol. 10, Núm. 6, pp. 1766-1781
2017
2016
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Inflammation, glucose, and vascular cell damage: The role of the pentose phosphate pathway
Cardiovascular Diabetology, Vol. 15, Núm. 1
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NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming
Cell Reports, Vol. 14, Núm. 8, pp. 1883-1891
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α-Ketoglutarate dehydrogenase complex moonlighting: ROS signalling added to the list: An Editorial highlight for ‘Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?’
Journal of Neurochemistry
2015
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DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating Pink1
Biochemical Journal, Vol. 467, Núm. 2, pp. 303-310
2014
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Abstract 560: Inflammation Converts Glucose Into A Deleterious Agent In Human Aortic Smooth Muscle Cells
Hypertension, Vol. 64, Núm. suppl_1
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Pink1 deficiency sustains cell proliferation by reprogramming glucose metabolism through hif1
Nature Communications, Vol. 5
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The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism
Journal of Neurochemistry, Vol. 129, Núm. 4, pp. 663-671
2013
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Underestimation of the pentose-phosphate pathway in intact primary neurons as revealed by metabolic flux analysis
Journal of Cerebral Blood Flow and Metabolism, Vol. 33, Núm. 12, pp. 1843-1845
2012
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Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration
Cell Death and Differentiation, Vol. 19, Núm. 10, pp. 1582-1589
2009
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The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
Nature Cell Biology, Vol. 11, Núm. 6, pp. 747-752
2006
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Lesión oxidativa de proteínas de hígado y corazón de rata durante el proceso de envejecimiento
Revista Espanola de Geriatria y Gerontologia, Vol. 41, Núm. 1, pp. 48-54
2005
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Inhibition of mitochondrial respiration by nitric oxide: Its role in glucose metabolism and neuroprotection
Journal of Neuroscience Research
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Intrinsically fluorescent cytotoxic cisplatin analogues as DNA marker molecules
Bioconjugate Chemistry, Vol. 16, Núm. 2, pp. 275-282
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Knockdown of glutamate-cysteine by ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons
Journal of Biological Chemistry, Vol. 280, Núm. 47, pp. 38992-39001