Publicaciones (148) Publicaciones de Eugenio Miguel Santos de Dios

2023

  1. Advances in Molecular Research of Oncogenes

    International Journal of Molecular Sciences

  2. Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors

    Oncogene, Vol. 42, Núm. 5, pp. 389-405

  3. Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma

    Nature Communications, Vol. 14, Núm. 1

  4. GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina

    Cells, Vol. 12, Núm. 21

  5. Optimized Protocol for Isolation and Culture of Murine Neonatal Primary Lung Fibroblasts

    Methods and Protocols, Vol. 6, Núm. 1

  6. PKD phosphorylation and COP9/Signalosome modulate intracellular Spry2 protein stability

    Oncogenesis, Vol. 12, Núm. 1

2022

  1. Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia

    Cancers, Vol. 14, Núm. 16

2021

  1. 40 years of RAS-a historic overview

    Genes, Vol. 12, Núm. 5

  2. Anthraquinones as inhibitors of SOS RAS-GEF activity

    Biomolecules, Vol. 11, Núm. 8

  3. Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis

    Oncogene, Vol. 40, Núm. 27, pp. 4538-4551

  4. Functional specificity of the members of the sos family of ras‐gef activators: Novel role of sos2 in control of epidermal stem cell homeostasis

    Cancers, Vol. 13, Núm. 9

  5. Ras GEF Mouse Models for the Analysis of Ras Biology and Signaling

    Methods in Molecular Biology (Humana Press Inc.), pp. 361-395

  6. Sos2 comes to the fore: Differential functionalities in physiology and pathology

    International Journal of Molecular Sciences, Vol. 22, Núm. 12

  7. The childhood-onset neurodegeneration with cerebellar atrophy (Condca) disease caused by agtpbp1 gene mutations: The purkinje cell degeneration mouse as an animal model for the study of this human disease

    Biomedicines, Vol. 9, Núm. 9

2020

  1. SOS GEFs in health and disease

    Biochimica et Biophysica Acta - Reviews on Cancer, Vol. 1874, Núm. 2

2019

  1. Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice

    Cell Death and Disease, Vol. 10, Núm. 11

  2. Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses

    Journal of Leukocyte Biology, Vol. 106, Núm. 4, pp. 815-822

  3. Nucleolin reorganization and nucleolar stress in Purkinje cells of mutant PCD mice

    Neurobiology of Disease, Vol. 127, pp. 312-322

  4. The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein

    Oncogenesis, Vol. 8, Núm. 1

2018

  1. Differential role of the RasGEFs Sos1 and Sos2 in mouse skin homeostasis and carcinogenesis

    Molecular and Cellular Biology, Vol. 38, Núm. 16