Eugenio Miguel
Santos de Dios
Profesor Emérito
Publications (149) Eugenio Miguel Santos de Dios publications
2024
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Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice
Cell Communication and Signaling, Vol. 22, Núm. 1
2023
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Advances in Molecular Research of Oncogenes
International Journal of Molecular Sciences
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
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Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma
Nature Communications, Vol. 14, Núm. 1
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GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina
Cells, Vol. 12, Núm. 21
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Optimized Protocol for Isolation and Culture of Murine Neonatal Primary Lung Fibroblasts
Methods and Protocols, Vol. 6, Núm. 1
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PKD phosphorylation and COP9/Signalosome modulate intracellular Spry2 protein stability
Oncogenesis, Vol. 12, Núm. 1
2022
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Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia
Cancers, Vol. 14, Núm. 16
2021
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40 years of RAS-a historic overview
Genes, Vol. 12, Núm. 5
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Anthraquinones as inhibitors of SOS RAS-GEF activity
Biomolecules, Vol. 11, Núm. 8
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Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis
Oncogene, Vol. 40, Núm. 27, pp. 4538-4551
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Functional specificity of the members of the sos family of ras‐gef activators: Novel role of sos2 in control of epidermal stem cell homeostasis
Cancers, Vol. 13, Núm. 9
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Ras GEF Mouse Models for the Analysis of Ras Biology and Signaling
Methods in Molecular Biology (Humana Press Inc.), pp. 361-395
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Sos2 comes to the fore: Differential functionalities in physiology and pathology
International Journal of Molecular Sciences, Vol. 22, Núm. 12
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The childhood-onset neurodegeneration with cerebellar atrophy (Condca) disease caused by agtpbp1 gene mutations: The purkinje cell degeneration mouse as an animal model for the study of this human disease
Biomedicines, Vol. 9, Núm. 9
2020
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SOS GEFs in health and disease
Biochimica et Biophysica Acta - Reviews on Cancer, Vol. 1874, Núm. 2
2019
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Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice
Cell Death and Disease, Vol. 10, Núm. 11
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Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses
Journal of Leukocyte Biology, Vol. 106, Núm. 4, pp. 815-822
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Nucleolin reorganization and nucleolar stress in Purkinje cells of mutant PCD mice
Neurobiology of Disease, Vol. 127, pp. 312-322
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The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein
Oncogenesis, Vol. 8, Núm. 1