Mercedes
Dosil Castro
Profesora Titular de Universidad
XOSE R.
GARCIA BUSTELO
Investigador
Publicaciones en las que colabora con XOSE R. GARCIA BUSTELO (21)
2024
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VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma
Scientific Reports, Vol. 14, Núm. 1
2023
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
2022
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A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
Cell Reports, Vol. 38, Núm. 11
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Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model
Molecular Oncology, Vol. 16, Núm. 19, pp. 3533-3553
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The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function
Oncogene, Vol. 41, Núm. 24, pp. 3341-3354
2021
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Efficient fractionation and analysis of ribosome assembly intermediates in human cells
RNA Biology, Vol. 18, Núm. S1, pp. 182-197
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New functions of vav family proteins in cardiovascular biology, skeletal muscle, and the nervous system
Biology, Vol. 10, Núm. 9
2020
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Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
Nature Communications, Vol. 11, Núm. 1
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Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor
Oncogene, Vol. 39, Núm. 28, pp. 5098-5111
2019
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Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms
Oncogene, Vol. 38, Núm. 2, pp. 209-227
2018
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Ribosome biogenesis and cancer: basic and translational challenges
Current Opinion in Genetics and Development, Vol. 48, pp. 22-29
2017
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Focal accumulation of preribosomes outside the nucleolus during metaphase-anaphase in budding yeast
RNA, Vol. 23, Núm. 9, pp. 1432-1443
2014
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Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease
Nature Communications, Vol. 5
2007
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The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism
Molecular and Cellular Biology, Vol. 27, Núm. 15, pp. 5414-5429
2005
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Control of lymphocyte shape and the chemotactic response by the GTP exchange factor Vav
Blood, Vol. 105, Núm. 8, pp. 3026-3034
2004
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Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle
Journal of Biological Chemistry, Vol. 279, Núm. 36, pp. 37385-37397
2002
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Structural determinants for the biological activity of Vav proteins
Journal of Biological Chemistry, Vol. 277, Núm. 47, pp. 45377-45392
2001
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How Vav proteins discriminate the GTPases Rac1 and Rhoa from Cdc42
Oncogene, Vol. 20, Núm. 56, pp. 8057-8065
1989
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The expression of prothymosin α gene in T lymphocytes and leukemic lymphoid cells is tied to lymphocyte proliferation
Journal of Biological Chemistry, Vol. 264, Núm. 15, pp. 8451-8454
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The levels of cytochrome c oxidase subunit II mRNA change during the rat T-cell development
BBA - Bioenergetics, Vol. 977, Núm. 3, pp. 341-343