Publicaciones (26) Publicaciones de María Delgado Esteban

2024

  1. Potent, selective and reversible hMAO-B inhibition by benzalphthalides: Synthesis, enzymatic and cellular evaluations and virtual docking and predictive studies

    Bioorganic Chemistry, Vol. 146

2021

  1. Preconditioning‐activated akt controls neuronal tolerance to ischemia through the mdm2–p53 pathway

    International Journal of Molecular Sciences, Vol. 22, Núm. 14

  2. Refocusing the Brain: New Approaches in Neuroprotection Against Ischemic Injury

    Neurochemical Research, Vol. 46, Núm. 1, pp. 51-63

2019

  1. The Neuronal Ischemic Tolerance Is Conditioned by the Tp53 Arg72Pro Polymorphism

    Translational Stroke Research, Vol. 10, Núm. 2, pp. 204-215

2018

  1. Single-nucleotide polymorphism 309T>G in the MDM2 promoter determines functional outcome after stroke

    Stroke, Vol. 49, Núm. 10, pp. 2437-2444

  2. The MDM2-p53 pathway is involved in preconditioning-induced neuronal tolerance to ischemia

    Scientific Reports, Vol. 8, Núm. 1

2017

  1. APC/CCdh1-Rock2 pathway controls dendritic integrity and memory

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 17, pp. 4513-4518

  2. Estudio de la Caspasa-3 en un modelo experimental de precondicionamiento isquémico neuronal en cultivo

    Farmajournal, Vol. 2, Núm. 1, pp. 121-131

2015

  1. Cdk5-mediated inhibition of APC/C-Cdh1 switches on the cyclin D1-Cdk4-pRb pathway causing aberrant S-phase entry of postmitotic neurons

    Scientific Reports, Vol. 5

  2. Regulation of Bcl-xL–ATP synthase interaction by mitochondrial cyclin B1–cyclin-dependent kinase-1 determines neuronal survival

    Journal of Neuroscience, Vol. 35, Núm. 25, pp. 9287-9301

2013

  1. APC/C-Cdh1 coordinates neurogenesis and cortical size during development

    Nature Communications, Vol. 4

2011

  1. The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke

    Journal of Experimental Medicine, Vol. 208, Núm. 3, pp. 429-437

2010

  1. Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: Assessment of the protective effects of glycoursodeoxycholic acid

    Journal of Neurochemistry, Vol. 112, Núm. 1, pp. 56-65

  2. Human neuroblastoma cells with MYCN amplification are selectively resistant to oxidative stress by transcriptionally up-regulating glutamate cysteine ligase

    Journal of Neurochemistry, Vol. 113, Núm. 4, pp. 819-825

2008

  1. Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

    EMBO Journal, Vol. 27, Núm. 20, pp. 2736-2745

  2. Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons

    Journal of Molecular Neuroscience, Vol. 34, Núm. 1, pp. 77-87

  3. Regulation of glycolysis and pentose-phosphate pathway by nitric oxide: Impact on neuronal survival

    Biochimica et Biophysica Acta - Bioenergetics, Vol. 1777, Núm. 7-8, pp. 789-793

2007

  1. Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3- kinase/Akt neuroprotective signaling pathway

    Journal of Neurochemistry, Vol. 102, Núm. 1, pp. 194-205

2005

  1. Inhibition of mitochondrial respiration by nitric oxide: Its role in glucose metabolism and neuroprotection

    Journal of Neuroscience Research

  2. Knockdown of glutamate-cysteine by ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons

    Journal of Biological Chemistry, Vol. 280, Núm. 47, pp. 38992-39001