Department: BIOLOGÍA CELULAR Y PATOLOGÍA

PhD school: NEUROCIENCIAS

Institute: INSTITUTO DE INVESTIGACIÓN BIOMÉDICA DE SALAMANCA

Institute: INSTITUTO DE NEUROCIENCIAS DE CASTILLA Y LEÓN

Area: Histology

Research group: NEUROBIOLOGÍA MOLECULAR DE LAS NEUROTROFINAS

Was part of these groups:

Email: arevalojc@usal.es

Personal web: https://diarium.usal.es/arevalojc/?lang=en

Doctor by the Universidad de Salamanca with the thesis Analisys structure-function of nerve growth factor receptor, trka 1999. Supervised by Dr. María del Pilar Pérez González, Dr. Dionisio Miguel Martín Zanca.

For the past 16 years, I have led my own laboratory at the Institute for Neuroscience Castilla y Leon (INCyL) at the University of Salamanca. Initially, I held a Ramón and Cajal position from 2007 to 2012, and subsequently, I transitioned to an Associate Professor position. During my tenure, my laboratory has received substantial recognition and funding support. In the early years, I obtained several grants, including a Marie Curie IRG (2008-2012), two NARSAD Young Investigator Grants (2007-2009 and 2009-2011). Then, I successfully secured additional 5 national grants from the Spanish Government from 2008 up to now, as well as several from the regional government. Furthermore, my involvement as a partner in a European Consortium funded by a grant from the European Commission FPVII program (PAINCAGE) from 2014 to 2017 has greatly enriched our research endeavors. In addition, in 2021 I was co-IP of an Art. 83 with ReNeuron LTD. The primary focus of my laboratory revolves around identifying the molecular mechanisms governing neurotrophin actions through the exploration of Trk receptor ubiquitination and various interactors of neurotrophin receptors. More recently, our interests have expanded to encompass the study of pain, neurodegenerative disorders, and neuropsychiatric conditions. We have fostered valuable collaborations with renowned laboratories both nationally [Marçal Vilar (Institute of Biomedicine, Valencia), Álvaro Villarroel (CSIC, Bilbao), Félix Viana (Insitute of Neurosciences Alicante), Ángel Pastor (University of Sevilla), Silvia Ginés and Jordi Alberch (University of Barcelona), Juan Pedro Bolaños (University of Salamanca)] and internationally [Moses Chao (New York University, USA), Lino Tessarollo (National Cancer Institute, USA), Ottavio Arancio (Columbia University, USA), Antonino Cattaneo (Scuola Normale Superiore Pisa, Italy), Simona Capsoni (Scuola Normale Superiore Pisa, Italy), Marzia Malcangio (King´s College London, UK), Sharad Kumar (University of South Australia, Australia), Sung Ok Yoon (Ohio University, USA)] further enhancing the scope and impact of our research. Since establishing myself as an independent investigator, my laboratory has contributed significantly to the field of neurotrophins and pain, resulting in the publication of 31 research papers, where I am the senior/corresponding author in 15 of them. Just recently, I served as a Guest Associate Editor for the Topic “Role of Neurotrophins and Their Receptors in Brain Development, Neurological Disorders and Nervous System Diseases” held by the Journal Frontiers in Molecular Neurosciences. Additionally, I am proud to be a coauthor of 3 patents that were licensed in 2015. Throughout my career, I have made a dedicated effort to nurture the next generation of researchers. To date, I have had the privilege of supervising and guiding 8 PhD students, 17 master's students, and 3 postdoctoral researchers for varying periods. This commitment to mentorship is a cornerstone of my laboratory's mission, emphasizing not only the advancement of scientific knowledge but also the development of emerging talents in the field. In recognition of our contributions, the laboratory was honored with the 2022 Award for the best publication related to pain by the Grünenthal Foundation, and for our innovative work, we earned the distinction of the best innovation project 2023 in Salamanca by El Mundo Castilla y León.