![Foto de Marina](/img/nophoto.png)
Marina
Holgado Madruga
Profesora Titular de Universidad
Publicaciones (32) Publicaciones de Marina Holgado Madruga
2023
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Intermediate Molecular Phenotypes to Identify Genetic Markers of Anthracycline-Induced Cardiotoxicity Risk
Cells, Vol. 12, Núm. 15
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The Role of GAB1 in Cancer
Cancers, Vol. 15, Núm. 16
2022
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Evolutionary Origins of Metabolic Reprogramming in Cancer
International journal of molecular sciences, Vol. 23, Núm. 20
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Pathophysiological Integration of Metabolic Reprogramming in Breast Cancer
Cancers, Vol. 14, Núm. 2
2014
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Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III
Cancer Research, Vol. 74, Núm. 4, pp. 1238-1249
2010
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Development of an EGFRvIII specific recombinant antibody
BMC Biotechnology, Vol. 10
2007
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The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation
Journal of Biological Chemistry, Vol. 282, Núm. 11, pp. 7758-7769
2006
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c-Jun NH2-terminal kinase 2α2 promotes the tumorigenicity of human glioblastoma cells
Cancer Research, Vol. 66, Núm. 20, pp. 10024-10031
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β1 integrins modulate cell adhesion by regulating insulin-like growth factor-II levels in the microenvironment
Cancer Research, Vol. 66, Núm. 1, pp. 331-342
2005
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Host adaptor proteins Gab1 and CrkII promote InIB-dependent entry of Listeria monocytogenes
Cellular Microbiology, Vol. 7, Núm. 3, pp. 443-457
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Identification of a specific domain responsible for JNK2α2 autophosphorylation
Journal of Biological Chemistry, Vol. 280, Núm. 11, pp. 9913-9920
2004
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Role of the Grb2-Associated Binder 1/SHP-2 Interaction in Cell Growth and Transformation
Cancer Research, Vol. 64, Núm. 6, pp. 2007-2015
2003
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Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors
Cancer Research, Vol. 63, Núm. 1, pp. 250-255
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Gab1 is an integrator of cell death versus cell survival signals in oxidative stress
Molecular and Cellular Biology, Vol. 23, Núm. 13, pp. 4471-4484
2002
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Elevated JNK activation contributes to the pathogenesis of human brain tumors
Oncogene, Vol. 21, Núm. 33, pp. 5038-5046
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Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors
American Journal of Pathology, Vol. 160, Núm. 2, pp. 441-447
2001
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Grb-2-associated binder-1 is involved in insulin-induced egr-1 gene expression through its phosphatidylinositol 3′-kinase binding site
DNA and Cell Biology, Vol. 20, Núm. 4, pp. 223-229
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The Gab1 Docking Protein Links the B Cell Antigen Receptor to the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and to the SHP2 Tyrosine Phosphatase
Journal of Biological Chemistry, Vol. 276, Núm. 15, pp. 12257-12265
2000
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The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase
Molecular and Cellular Biology, Vol. 20, Núm. 22, pp. 8513-8525
1999
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A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis
Journal of Biological Chemistry, Vol. 274, Núm. 44, pp. 31719-31726