Consuelo
Gajate Fraile
Researcher in the period 2014-2015
Faustino
Mollinedo García
Researcher in the period 2014-2015
Publications by the researcher in collaboration with Faustino Mollinedo García (20)
2021
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Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents
European Journal of Medicinal Chemistry, Vol. 209
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Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release
Scientific Reports, Vol. 11, Núm. 1
2020
2017
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Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine
PLoS Neglected Tropical Diseases, Vol. 11, Núm. 8
2016
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Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy
Pharmacology and Therapeutics, Vol. 165, pp. 114-131
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The alkylphospholipid edelfosine shows activity against Strongyloides venezuelensis and induces apoptosis-like cell death
Acta Tropica, Vol. 162, pp. 180-187
2015
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Eficacia de alquil-fosfolípidos frente a Strongyloides venezuelensis
XIX Congreso de la Sociedad Española de Parasitología (SOCEPA)
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Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosine
Oncotarget, Vol. 6, Núm. 16, pp. 14596-14613
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Lipid raft-mediated Fas/CD95 apoptotic signaling in leukemic cells and normal leukocytes and therapeutic implications
Journal of Leukocyte Biology, Vol. 98, Núm. 5, pp. 739-759
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Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling
Apoptosis, Vol. 20, Núm. 5, pp. 584-606
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Lipid rafts as major platforms for signaling regulation in cancer
Advances in Biological Regulation, Vol. 57, pp. 130-146
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Triggers and signaling cross-talk controlling cell death commitment
Cell Cycle
2014
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Lipid rafts, endoplasmic reticulum and mitochondria in the antitumor action of the alkylphospholipid analog edelfosine
Anti-Cancer Agents in Medicinal Chemistry, Vol. 14, Núm. 4, pp. 509-527
2013
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Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast
Journal of Biological Chemistry, Vol. 288, Núm. 12, pp. 8405-8418
2012
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Apoptotic mechanisms are involved in the death of Strongyloides venezuelensis after triggering of nitric oxide
Parasite Immunology, Vol. 34, Núm. 12, pp. 570-580
2009
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Novel anti-inflammatory action of edelfosine lacking toxicity with protective effect in experimental colitis
Journal of Pharmacology and Experimental Therapeutics, Vol. 329, Núm. 2, pp. 439-449
2008
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Aplidin, a marine organism-derived compound with potent antimyeloma activity in vitro and in vivo
Cancer Research, Vol. 68, Núm. 13, pp. 5216-5225
2005
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Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety
Journal of Medicinal Chemistry, Vol. 48, Núm. 2, pp. 556-568
2004
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Synthesis and Biological Evaluation of New Selective Cytotoxic Cyclolignans Derived from Podophyllotoxin
Journal of Medicinal Chemistry, Vol. 47, Núm. 5, pp. 1214-1222
1998
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Physiological activation of human neutrophils down-regulates CD53 cell surface antigen
Journal of Leukocyte Biology, Vol. 63, Núm. 6, pp. 699-706