DAVID
JIMENO GARCÍA
Researcher from 2009
Publications (27) DAVID JIMENO GARCÍA publications
2024
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Randomised, double-blind, placebo-controlled, parallel-group, multicentric, phase IIA clinical trial for evaluating the safety, tolerability, and therapeutic efficacy of daily oral administration of NFX88 to treat neuropathic pain in individuals with spinal cord injury
Spinal Cord, Vol. 62, Núm. 8, pp. 454-467
2023
2019
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A Nucleotide-Dependent Conformational Switch Controls the Polymerization of Human IMP Dehydrogenases to Modulate their Catalytic Activity
Journal of Molecular Biology, Vol. 431, Núm. 5, pp. 956-969
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Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice
Cell Death and Disease, Vol. 10, Núm. 11
2018
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Differential role of the RasGEFs Sos1 and Sos2 in mouse skin homeostasis and carcinogenesis
Molecular and Cellular Biology, Vol. 38, Núm. 16
2017
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A new functional role uncovered for RASGRF2 in control of nuclear migration in cone photoreceptors during postnatal retinal development
Small GTPases
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Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus
Molecular and Cellular Neuroscience, Vol. 85, pp. 127-147
2016
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RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors
Journal of Cell Science, Vol. 129, Núm. 4, pp. 729-742
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Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs
Oncogene, Vol. 35, Núm. 50, pp. 6389-6402
2015
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CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium
Scientific Reports, Vol. 5
2013
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Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival
Molecular and Cellular Biology, Vol. 33, Núm. 22, pp. 4562-4578
2012
2010
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Dysfunction of heterotrimeric kinesin-2 in rod photoreceptor cells and the role of opsin mislocalization in rapid cell death
Molecular Biology of the Cell, Vol. 21, Núm. 23, pp. 4076-4088
2006
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Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre
Investigative Ophthalmology and Visual Science, Vol. 47, Núm. 11, pp. 5039-5046
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In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse
Human Molecular Genetics, Vol. 15, Núm. 11, pp. 1847-1857
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Kinesin-2 and photoreceptor cell death: Requirement of motor subunits
Experimental Eye Research, Vol. 82, Núm. 2, pp. 351-353
2005
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Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin
Nature Genetics, Vol. 37, Núm. 3, pp. 282-288
2003
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The degenerative and regenerative processes after the elimination of the proliferative peripheral retina of fish
Experimental Neurology, Vol. 179, Núm. 2, pp. 210-228
2002
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The glial design of a teleost optic nerve head supporting continuous growth
Journal of Histochemistry and Cytochemistry, Vol. 50, Núm. 10, pp. 1289-1302
2001
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Detection of macroglial cells in the fish optic nerve by intracellular injection in fixed tissue
European Journal of Anatomy, Vol. 5, Núm. 2, pp. 89-95