FISIOLOGÍA Y FARMACOLOGÍA
Departamento
MANUEL
MEDARDE AGUSTÍN
Investigador en el periodo 1984-2021
Publicaciones en las que colabora con MANUEL MEDARDE AGUSTÍN (16)
2019
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The Masked Polar Group Incorporation (MPGI) Strategy in Drug Design: Effects of Nitrogen Substitutions on Combretastatin and Isocombretastatin Tubulin Inhibitors
Molecules (Basel, Switzerland), Vol. 24, Núm. 23
2007
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Inhibition of the intestinal absorption of bile acids using cationic derivatives: Mechanism and repercussions
Biochemical Pharmacology, Vol. 73, Núm. 3, pp. 394-404
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Novel bile acid derivatives (BANBs) with cytostatic activity obtained by conjugation of their side chain with nitrogenated bases
Biochemical Pharmacology, Vol. 73, Núm. 9, pp. 1394-1404
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Novel cationic and neutral glycocholic acid and polyamine conjugates able to inhibit transporters involved in hepatic and intestinal bile acid uptake
Bioorganic and Medicinal Chemistry, Vol. 15, Núm. 6, pp. 2359-2367
2005
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Intrinsically fluorescent cytotoxic cisplatin analogues as DNA marker molecules
Bioconjugate Chemistry, Vol. 16, Núm. 2, pp. 275-282
2003
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Physiological characteristics of allo-cholic acid
Journal of Lipid Research, Vol. 44, Núm. 1, pp. 84-92
2001
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Structural characterization and cytostatic activity of chlorobischolylglycinatogold(III)
Journal of Inorganic Biochemistry, Vol. 84, Núm. 3-4, pp. 287-292
2000
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Antihypertensive activity of substituted 2,3,8,8a-tetrahydro-7H-oxazolo[3,2-a]pyridinedicarboxylate enantiomers
Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 4, pp. 319-322
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Structural characterization, kinetic studies, and in vitro biological activity of new cis-diamminebis-cholylglycinate(O,O') Pt(II) and cis-diamminebis-ursodeoxycholate(O,O') Pt(II) complexes
Bioconjugate Chemistry, Vol. 11, Núm. 2, pp. 167-174
1999
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Synthesis and characterization of sodium cis-dichlorochenodeoxycholylglycinato(O,N) platinum(II)- Cytostatic activity
BioMetals, Vol. 12, Núm. 3, pp. 281-288
1997
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Antihypertensive effect of some oxazolo[3,2-a]pyridines, thiazolo[3,2-a]pyridines and pyrido[2,1-b]oxazines in conscious spontaneously hypertensive rats
Journal of Pharmacy and Pharmacology, Vol. 49, Núm. 4, pp. 421-425
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Synthesis and characterization of a new bile acid and platinum(II) complex with cytostatic activity
Journal of Lipid Research, Vol. 38, Núm. 5, pp. 1022-1032
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Synthesis and characterization of the new cytostatic complex cis-diammineplatinum(II)-chlorocholylglycinate
Bioconjugate Chemistry, Vol. 8, Núm. 4, pp. 453-458
1996
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Synthesis and characterization of thiourea derivatives of α-aminoacids. crystal structure of methyl L-valinate and L-leucinate derivatives
Tetrahedron, Vol. 52, Núm. 17, pp. 6233-6240
1990
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Novel chelates of Pd(II) dithiocarbamates. Spectroscopic studies and thermal behaviour
Inorganica Chimica Acta, Vol. 174, Núm. 1, pp. 67-75
1989
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New PtS4 chromophores of dithiocarbamates derived from α-amino acids: synthesis, characterization and thermal behaviour
Inorganica Chimica Acta, Vol. 160, Núm. 1, pp. 37-42