MICROBIOLOGÍA Y GENÉTICA
UnidadVista.TipoUnidadOrganizativaVista(nombre=Department, nombrePlural=Departments)

Luis Francisco
Lorenzo Martín
Publications by the researcher in collaboration with Luis Francisco Lorenzo Martín (11)
2023
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
2022
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The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function
Oncogene, Vol. 41, Núm. 24, pp. 3341-3354
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Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model
Molecular Oncology, Vol. 16, Núm. 19, pp. 3533-3553
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A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
Cell Reports, Vol. 38, Núm. 11
2021
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Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis
EMBO Journal, Vol. 40, Núm. 22
2020
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Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor
Oncogene, Vol. 39, Núm. 28, pp. 5098-5111
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Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis
Nature Communications, Vol. 11, Núm. 1
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VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma
Nature Communications, Vol. 11, Núm. 1
2019
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Vagal afferents contribute to sympathoexcitation-driven metabolic dysfunctions
Journal of Endocrinology, Vol. 240, Núm. 3, pp. 483-496
2018
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Differential role of the RasGEFs Sos1 and Sos2 in mouse skin homeostasis and carcinogenesis
Molecular and Cellular Biology, Vol. 38, Núm. 16
2017
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A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia
Cancer Cell, Vol. 32, Núm. 5, pp. 608-623.e9