BIOLOGÍA FUNCIONAL Y GENÓMICA
Escuela de doctorado
María Ángeles
Almeida Parra
Profesora Asociada
Publicaciones en las que colabora con María Ángeles Almeida Parra (86)
2024
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Weak neuronal glycolysis sustains cognition and organismal fitness
Nature Metabolism
2023
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Brightness and shadows of mitochondrial ROS in the brain
Neurobiology of Disease, Vol. 184
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Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation
Essays in biochemistry, Vol. 67, Núm. 1, pp. 17-26
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Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognition
Nature Metabolism, Vol. 5, Núm. 8, pp. 1290-1302
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Mitochondrial sodium/calcium exchanger NCLX regulates glycolysis in astrocytes, impacting on cognitive performance
Journal of Neurochemistry, Vol. 165, Núm. 4, pp. 521-535
2022
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APC/C-Cdh1-targeted substrates as potential therapies for Alzheimer’s disease
Frontiers in Pharmacology
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Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis
Nature Communications, Vol. 13, Núm. 1
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Amyloid-β Induces Cdh1-Mediated Rock2 Stabilization Causing Neurodegeneration
Frontiers in Pharmacology, Vol. 13
2021
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Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour
Redox Biology, Vol. 41
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Preconditioning‐activated akt controls neuronal tolerance to ischemia through the mdm2–p53 pathway
International Journal of Molecular Sciences, Vol. 22, Núm. 14
2020
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Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke
Science advances, Vol. 6, Núm. 41
2019
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Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization
Neuropharmacology, Vol. 146, pp. 19-27
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Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour
Nature Metabolism
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Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice
Scientific Reports, Vol. 9, Núm. 1
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The Neuronal Ischemic Tolerance Is Conditioned by the Tp53 Arg72Pro Polymorphism
Translational Stroke Research, Vol. 10, Núm. 2, pp. 204-215
2018
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Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function
Redox Biology, Vol. 19, pp. 52-61
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Single-nucleotide polymorphism 309T>G in the MDM2 promoter determines functional outcome after stroke
Stroke, Vol. 49, Núm. 10, pp. 2437-2444
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The MDM2-p53 pathway is involved in preconditioning-induced neuronal tolerance to ischemia
Scientific Reports, Vol. 8, Núm. 1
2017
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APC/CCdh1-Rock2 pathway controls dendritic integrity and memory
Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 17, pp. 4513-4518
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Mitochondrial Complex I Activity is Conditioned by Supercomplex I–III2–IV Assembly in Brain Cells: Relevance for Parkinson’s Disease
Neurochemical Research, Vol. 42, Núm. 6, pp. 1676-1682