Publications in collaboration with researchers from Eli Lilly and Company (14)

2017

  1. Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences

    Journal of Medicinal Chemistry, Vol. 60, Núm. 23, pp. 9807-9820

2009

  1. Organocatalytic synthesis of an alkyltetrahydropyran

    Synlett, pp. 390-394

2005

  1. 2-Alkoxydihydrocinnamates as PPAR agonists. Activity modulation by the incorporation of phenoxy substituents

    Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 1, pp. 51-55

  2. Chemistry of allylsulfones: A new preparation of N-diphenylmethylene-2- vinyl-substituted cyclopropylamines

    Synlett, pp. 158-160

  3. Chemistry of sulfones: Synthesis of a new chiral nucleophilic catalyst

    Tetrahedron Asymmetry, Vol. 16, Núm. 17, pp. 2980-2985

  4. Chemistry of vinyl sulfones. Approach to novel conformationally restricted analogues of glutamic acid

    Tetrahedron, Vol. 61, Núm. 3, pp. 699-707

  5. Synthesis of tri- and tetracyclic diterpenes. Cyclisations promoted by SmI 2

    Tetrahedron, Vol. 61, Núm. 4, pp. 977-1003

  6. Vinylsulfones as nucleophiles and Michael acceptors in the same step: Stereoselective synthesis of amino acid precursors

    Synthesis, pp. 3327-3334

  7. Vinylsulfones versus alkylsulfones in the addition to chiral imines. Synthesis of N-(tert-butoxycarbonyl)-L-homophenylalanine

    Tetrahedron, Vol. 61, Núm. 49, pp. 11641-11648

2004

  1. (2S,1′S,2′R,3′R)-2-(2′-Carboxy-3′ -hydroxymethylcyclopropyl) Glycine Is a Highly Potent Group 2 and 3 Metabotropic Glutamate Receptor Agonist with Oral Activity

    Journal of Medicinal Chemistry, Vol. 47, Núm. 2, pp. 456-466

2003

  1. Chemistry of Epoxysulfones: Straightforward Synthesis of Versatile Chiral Building Blocks

    Organic Letters, Vol. 5, Núm. 23, pp. 4361-4364

  2. Stereocontrolled synthesis of cyclopropanol amino acids from allylic sulfones: Conformationally restricted building blocks

    Organic Letters, Vol. 5, Núm. 20, pp. 3687-3690

  3. Synthesis of bioactive sesterterpenolides from ent-halimic acid. 15-Epi-ent-cladocoran A and B

    Journal of Organic Chemistry, Vol. 68, Núm. 19, pp. 7496-7504

1995

  1. Conformationally constrained ACPD analogues. Synthesis and resolution of 3-aminobicyclo[3,3,0]octane-1,3-dicarboxylic acids

    Tetrahedron, Vol. 51, Núm. 11, pp. 3271-3278