FARMACIA Y SALUD
Escuela de doctorado
Centro de Investigaciones Biológicas
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro de Investigaciones Biológicas (18)
2021
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Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents
European Journal of Medicinal Chemistry, Vol. 209
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New diarylsulfonamide inhibitors of Leishmania infantum amastigotes
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 16, pp. 45-64
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New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure–activity relationships, and molecular modelling
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 2025-2044
2020
2019
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Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target
Medicinal Research Reviews, Vol. 39, Núm. 3, pp. 775-830
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Imidazo[2,1-a]isoindole scaffold as an uncharted structure active on Leishmania donovani
European Journal of Medicinal Chemistry, Vol. 182
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The Masked Polar Group Incorporation (MPGI) Strategy in Drug Design: Effects of Nitrogen Substitutions on Combretastatin and Isocombretastatin Tubulin Inhibitors
Molecules (Basel, Switzerland), Vol. 24, Núm. 23
2018
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Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells
European Journal of Medicinal Chemistry, Vol. 158, pp. 167-183
2016
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Dietary and microbiome factors determine longevity in Caenorhabditis elegans
Aging, Vol. 8, Núm. 7, pp. 1513-1539
2015
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Mechanisms of action of substituted β-amino alkanols on leishmania donovani
Antimicrobial Agents and Chemotherapy, Vol. 59, Núm. 2, pp. 1211-1218
2014
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Impaired wound repair in adult endoglin heterozygous mice associated with lower NO bioavailability
Journal of Investigative Dermatology, Vol. 134, Núm. 1, pp. 247-255
2013
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Endowing indole-based tubulin inhibitors with an anchor for derivatization: Highly potent 3-substituted indolephenstatins and indoleisocombretastatins
Journal of Medicinal Chemistry, Vol. 56, Núm. 7, pp. 2813-2827
2012
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Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins
Journal of Medicinal Chemistry, Vol. 55, Núm. 15, pp. 6724-6737
2006
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Endoglin regulates cyclooxygenase-2 expression and activity
Circulation Research, Vol. 99, Núm. 3, pp. 248-256
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Reduced angiogenic responses in adult endoglin heterozygous mice
Cardiovascular Research, Vol. 69, Núm. 4, pp. 845-854
2005
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Temporal changes in renal endoglin and TGF-β1 expression following ureteral obstruction in rats
Journal of Physiology and Biochemistry, Vol. 61, Núm. 3, pp. 457-467
2001
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Up-regulation of endoglin, a TGF-β-binding protein, in rats with experimental renal fibrosis induced by renal mass reduction
Nephrology Dialysis Transplantation, Vol. 16, Núm. SUPPL. 1, pp. 34-39
2000
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Design, synthesis and cytotoxic activities of naphthyl analogues of combretastatin A-4
Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 22, pp. 2549-2551