Búsqueda de bacterias productoras de antibióticos a partir del culturoma rizosférico

  1. Fernández-Villacorta, Noelia 1
  2. Mateos, Pedro F. 1
  3. Saati-Santamaría, Zaki 1
  1. 1 Universidad de Salamanca
    info

    Universidad de Salamanca

    Salamanca, España

    ROR https://ror.org/02f40zc51

Aldizkaria:
Farmajournal

ISSN: 2445-1355

Argitalpen urtea: 2020

Alea: 5

Zenbakia: 2

Orrialdeak: 43-50

Mota: Artikulua

DOI: 10.14201/FJ2020524350 DIALNET GOOGLE SCHOLAR lock_openSarbide irekia editor

Beste argitalpen batzuk: Farmajournal

Laburpena

The inappropriate use of antibiotics has increased the number illnesses and deaths because of multidrug resistant microbial caused infections. The objective of this study was to isolate rhizospheric bacteria and evaluate their potential to produce antimicrobial compounds. 418 bacterial colonies were isolated and assayed against bacteria and fungi in order to analyze their antimicrobial potential, finding 114 antimicrobial producing strains. Two of these strains with best antimicrobial spectrum of action were selected for further analyses, and were identified as Bacillus albus and Streptomycs cirratus. Their genomes were sequenced and secondary metabolism pathways were analyzed, finding genetic machinery potentially implicated in the production of new bioactive compounds.

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