Publications dans lesquelles il/elle collabore avec MANUEL MEDARDE AGUSTÍN (72)

2019

  1. The Masked Polar Group Incorporation (MPGI) Strategy in Drug Design: Effects of Nitrogen Substitutions on Combretastatin and Isocombretastatin Tubulin Inhibitors

    Molecules (Basel, Switzerland), Vol. 24, Núm. 23

2016

  1. Pyridine based antitumour compounds acting at the colchicine site

    Current Medicinal Chemistry, Vol. 23, Núm. 11, pp. 1100-1130

2015

  1. Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para -nitrogen substituted isocombretastatins

    European Journal of Medicinal Chemistry, Vol. 100, pp. 210-222

2011

  1. Synthesis of novel polynitrogenated drugs based on phenstatins. Tubulin polymerization evaluation

    4TH EUROPEAN CONFERENCE ON CHEMISTRY FOR LIFE SCIENCES

2010

  1. Exploring the effect of 2,3,4-trimethoxy-phenyl moiety as a component of indolephenstatins

    European Journal of Medicinal Chemistry, Vol. 45, Núm. 2, pp. 588-597

2008

  1. Diarylmethyloxime and hydrazone derivatives with 5-indolyl moieties as potent inhibitors of tubulin polymerization

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 11, pp. 5952-5961

  2. Imino-Diels-Alder reactions of 1-aryl-3-(trialkylsiloxy)-1,3-butadienes in solution and the solid phase

    European Journal of Organic Chemistry, pp. 4004-4014

  3. Naphthylphenstatins as tubulin ligands: Synthesis and biological evaluation

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 19, pp. 8999-9008

2007

  1. Conformationally restricted macrocyclic analogues of combretastatins

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 22, pp. 6316-6320

  2. New nitrogenated siloxy butadienes from 1,3-dichloroacetone

    Tetrahedron Letters, Vol. 48, Núm. 6, pp. 907-910

  3. Synthesis and biological activity of naphthalene analogues of phenstatins: Naphthylphenstatins

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 12, pp. 3417-3420

2006

  1. Reactivity of 4-tert-butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with hydrazines

    Molecules, Vol. 11, Núm. 11, pp. 929-939

2005

  1. Diels-Alder reactivity of 4-aryl-1-phthalimido-2-siloxy-1,3-butadienes

    Tetrahedron, Vol. 61, Núm. 28, pp. 6871-6878

  2. Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety

    Journal of Medicinal Chemistry, Vol. 48, Núm. 2, pp. 556-568

  3. New naphthylcombretastatins. Modifications on the ethylene bridge

    Bioorganic and Medicinal Chemistry, Vol. 13, Núm. 6, pp. 2097-2107

  4. New synthesis of arcyriaflavin-A via silyl enol ether-mediated and Fischer indolisations

    Tetrahedron Letters, Vol. 46, Núm. 29, pp. 4839-4841

  5. Stilbenophane analogues of deoxycombretastatin A-4

    Journal of Organic Chemistry, Vol. 70, Núm. 16, pp. 6544-6547

  6. Synthesis of a conformationally restricted polyoxygenated crownophane

    Tetrahedron Letters, Vol. 46, Núm. 41, pp. 7055-7057

2004

  1. 1-Phthalimido-4-(3-indolyl)-2-siloxy-1,3-butadienes: Synthesis and Diels-Alder reactivity

    Tetrahedron Letters, Vol. 45, Núm. 8, pp. 1631-1634

  2. A new family of quinoline and quinoxaline analogues of combretastatins

    Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 14, pp. 3771-3774