Raquel
Álvarez Lozano
Profesora Titular de Universidad
Rafael
Peláez Lamamie de Claira Arroyo
Profesor Titular de Universidad
Publicaciones en las que colabora con Rafael Peláez Lamamie de Claira Arroyo (26)
2024
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Experimental structure based drug design (SBDD) applications for anti-leishmanial drugs: A paradigm shift?
Medicinal Research Reviews, Vol. 44, Núm. 3, pp. 1055-1120
2023
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Frentizole, a Nontoxic Immunosuppressive Drug, and Its Analogs Display Antitumor Activity via Tubulin Inhibition
International Journal of Molecular Sciences, Vol. 24, Núm. 24
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Novel amino analogs of the trimethoxyphenyl ring in potent colchicine site ligands improve solubility by the masked polar group incorporation (MPGI) strategy
Bioorganic Chemistry, Vol. 131
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Nuevos antitumorales y antiparasitarios de naturaleza híbrida para la formación de nanopartículas
IX Jornadas de investigadoras de Castilla y León
2021
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Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents
European Journal of Medicinal Chemistry, Vol. 209
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Microtubule destabilizing sulfonamides as an alternative to taxane-based chemotherapy
International Journal of Molecular Sciences, Vol. 22, Núm. 4, pp. 1-21
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New diarylsulfonamide inhibitors of Leishmania infantum amastigotes
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 16, pp. 45-64
2020
2019
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Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target
Medicinal Research Reviews, Vol. 39, Núm. 3, pp. 775-830
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Design, Synthesis and Biological Evaluation of Benzodiazepines Analogues as Anti-Tubuling Agents
FarmaJournal
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Diseño, síntesis y evaluación de amidas y sulfonamidas con actividad tipo colchicina contra Strongyloides venezuelensis
XI Congreso de la Sociedad Española de Medicina Tropical y Salud Internacional (SEMTSI)
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The Masked Polar Group Incorporation (MPGI) Strategy in Drug Design: Effects of Nitrogen Substitutions on Combretastatin and Isocombretastatin Tubulin Inhibitors
Molecules (Basel, Switzerland), Vol. 24, Núm. 23
2018
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Bioactive Heterometallic CuII-ZnII Complexes with Potential Biomedical Applications
ACS Omega, Vol. 3, Núm. 10, pp. 13343-13353
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Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells
European Journal of Medicinal Chemistry, Vol. 158, pp. 167-183
2016
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Pyridine based antitumour compounds acting at the colchicine site
Current Medicinal Chemistry, Vol. 23, Núm. 11, pp. 1100-1130
2015
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Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para -nitrogen substituted isocombretastatins
European Journal of Medicinal Chemistry, Vol. 100, pp. 210-222
2014
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New ligands of the tubulin colchicine site based on X-ray structures
Current Topics in Medicinal Chemistry, Vol. 14, Núm. 20, pp. 2231-2252
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P, p -dihydroxydihydrostilbenophanes related to antimitotic combretastatins. Conformational analysis and its relationship to tubulin Inhibition
Journal of Organic Chemistry, Vol. 79, Núm. 15, pp. 6840-6857
2013
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Endowing indole-based tubulin inhibitors with an anchor for derivatization: Highly potent 3-substituted indolephenstatins and indoleisocombretastatins
Journal of Medicinal Chemistry, Vol. 56, Núm. 7, pp. 2813-2827
2011
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New para-para stilbenophanes: Synthesis by mcmurry coupling, conformational analysis and inhibition of tubulin polymerisation
Chemistry - A European Journal, Vol. 17, Núm. 12, pp. 3406-3419